HitPredict

Interactor 1: TAU (P10636)
Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau)
Gene: MAPT

Interactor 2: WDR7 (Q9Y4E6)
WD repeat-containing protein 7 (Rabconnectin-3 beta) (TGF-beta resistance-associated protein TRAG)
Gene: WDR7

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	35063084
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 758 Hs			1 1490
+	Mm
		498109 TAU_MOUSE (1-758): 1.4e-69: 244: 70.17		WDR7_MOUSE (1-1490): 0: 1503: 93.31
+	Rn
		582034 TAU_RAT (1-758): 4.86e-75: 260: 71.47		WDR7_RAT (1-1490): 0: 1487: 92.84
+	Rn
		94260 F1LST4_RAT (1-757): 8.59e-75: 260: 71.56		WDR7_RAT (1-1490): 0: 1487: 92.84
+	Hs
		496503 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		LIS1_HUMAN (638-893): 1.28e-33: 137: 10.83
+	Dm
		52421 X2JDJ3_DROME (62-753): 1.93e-12: 73.2: 9.96		A1Z7J7_DROME (346-1157): 1.13e-87: 315: 12.57
+	Hs
		497284 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		WDR17_HUMAN (25-271): 1.58e-09: 64.9: 15.20
+	Mm
		497983 TAU_MOUSE (1-758): 1.4e-69: 244: 70.17		GNB5_MOUSE (455-635): 5.87e-19: 93: 16.00
+	Hs
		653951 MAP4_HUMAN (3-742): 6.73e-32: 135: 20.56		WDR5_HUMAN (16-237): 2.88e-33: 134: 13.90
+	Hs
		152622 KMT2D_HUMAN (226-636): 8.62e-26: 116: 19.55		WDR5_HUMAN (16-237): 2.88e-33: 134: 13.90
+	Hs
		152663 KMT2D_HUMAN (226-636): 8.62e-26: 116: 19.55		WDR5B_HUMAN (16-237): 5.58e-32: 130: 13.00
+	Hs
		209436 MDC1_HUMAN (2-755): 3.72e-28: 124: 8.57		PLRG1_HUMAN (155-433): 1.44e-15: 83.7: 8.22
+	Mm
		903669 KMT2C_MOUSE (228-587): 6.06e-09: 61.9: 16.84		WDR5_MOUSE (16-237): 2.88e-33: 134: 13.90
+	Hs
		903374 KMT2C_HUMAN (83-649): 6.28e-09: 61.8: 12.91		WDR5_HUMAN (16-237): 2.88e-33: 134: 13.90