HitPredict

Interactor 1: TAU (P10636)
Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau)
Gene: MAPT

Interactor 2: HYOU1 (Q9Y4L1)
Hypoxia up-regulated protein 1 (150 kDa oxygen-regulated protein) (ORP-150) (170 kDa glucose-regulated protein) (GRP-170) (Heat shock protein family H member 4)
Gene: HYOU1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	35063084
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005576 - extracellular region GO:0051087 - protein-folding chaperone binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 758 Hs			1 999
+	Hs
		497367 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		HS105_HUMAN (33-960): 0: 812: 24.46
+	Mm
		498021 TAU_MOUSE (1-758): 1.4e-69: 244: 70.17		Q3U2G2_MOUSE (33-964): 0: 855: 25.32
+	Hs
		320800 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		HS74L_HUMAN (33-960): 0: 793: 24.57
+	Hs
		496426 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		HSP74_HUMAN (33-964): 0: 785: 25.64
+	Mm
		498049 TAU_MOUSE (1-758): 1.4e-69: 244: 70.17		HS105_MOUSE (33-970): 0: 818: 24.84
+	Rn
		291980 TAU_RAT (1-758): 4.86e-75: 260: 71.47		HSP74_RAT (33-964): 0: 787: 25.53
+	Rn
		94108 F1LST4_RAT (1-757): 8.59e-75: 260: 71.56		HSP74_RAT (33-964): 0: 787: 25.53
+	Mm
		497946 TAU_MOUSE (1-758): 1.4e-69: 244: 70.17		HS74L_MOUSE (33-955): 0: 796: 25.24
+	Hs
		654083 MAP4_HUMAN (3-742): 6.73e-32: 135: 20.56		HYOU1_HUMAN (1-999): 0: 859: 100.00
+	Hs
		554275 MUC1_HUMAN (242-751): 2.66e-25: 114: 10.84		HSP74_HUMAN (33-964): 0: 785: 25.64
+	Hs
		496425 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		HS71L_HUMAN (682-814): 9.92e-31: 131: 15.04
+	Hs
		496165 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		HSP7C_HUMAN (682-815): 2.07e-30: 130: 16.42
+	Hs
		483743 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		HS71A_HUMAN (682-813): 3.35e-30: 129: 16.67
+	Hs
		496637 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		HSP72_HUMAN (682-814): 8.57e-30: 128: 16.54
+	Hs
		496242 TAU_HUMAN (1-758): 3.6e-89: 298: 100.00		HSP76_HUMAN (682-813): 1.1e-27: 121: 19.70
+	Mm
		497918 TAU_MOUSE (1-758): 1.4e-69: 244: 70.17		HS71L_MOUSE (682-816): 7.39e-31: 131: 15.56
+	Mm
		497989 TAU_MOUSE (1-758): 1.4e-69: 244: 70.17		HSP7C_MOUSE (682-815): 1.96e-30: 130: 16.42
+	Mm
		497919 TAU_MOUSE (1-758): 1.4e-69: 244: 70.17		HSP72_MOUSE (682-814): 2.4e-29: 126: 15.79
+	Mm
		498048 TAU_MOUSE (1-758): 1.4e-69: 244: 70.17		HS71A_MOUSE (682-813): 1.62e-28: 124: 15.91
+	Hs
		503487 MAP4_HUMAN (3-742): 6.73e-32: 135: 20.56		HSP7C_HUMAN (682-815): 2.07e-30: 130: 16.42