HitPredict

Interactor 1: TAU (P10637)
Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau)
Gene: Mapt

Interactor 2: COF1 (P18760)
Cofilin-1 (Cofilin, non-muscle isoform)
Gene: Cfl1

Species: Mus musculus

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	30068389
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005576 - extracellular region GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0030426 - growth cone GO:0043025 - neuronal cell body
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 733 Mm			1 166
+	Mm
		498155 TAU_MOUSE (1-733): 4.79e-86: 288: 100.00		DEST_MOUSE (1-166): 4.46e-71: 213: 70.48
+	Rn
		581943 TAU_RAT (1-733): 1.67e-78: 268: 88.46		COF1_RAT (1-166): 2.75e-74: 221: 99.40
+	Rn
		94167 F1LST4_RAT (1-732): 4.29e-78: 268: 88.58		COF1_RAT (1-166): 2.75e-74: 221: 99.40
+	Hs
		496321 TAU_HUMAN (1-733): 3.71e-62: 224: 69.50		COF1_HUMAN (1-166): 2.55e-74: 221: 98.80
+	Hs
		497833 TAU_HUMAN (1-733): 3.71e-62: 224: 69.50		COF2_HUMAN (1-166): 1.1e-72: 217: 80.72
+	Hs
		496692 TAU_HUMAN (1-733): 3.71e-62: 224: 69.50		DEST_HUMAN (1-166): 7.44e-70: 210: 71.08
+	Hs
		496930 TAU_HUMAN (1-733): 3.71e-62: 224: 69.50		TWF1_HUMAN (3-144): 1.12e-33: 123: 22.07
+	Dm
		799778 Q9VLS7_DROME (23-733): 1.82e-11: 70.1: 10.76		CADF_DROME (1-153): 3.24e-37: 126: 33.33