HitPredict

Interactor 1: TAU (P10637)
Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau)
Gene: Mapt

Interactor 2: ACTC (P68033)
Actin, alpha cardiac muscle 1 (EC 3.6.4.-) (Alpha-cardiac actin) [Cleaved into: Actin, alpha cardiac muscle 1, intermediate form]
Gene: Actc1

Species: Mus musculus

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	30068389
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0044297 - cell body
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 733 Mm			1 377
+	Hs
		496683 TAU_HUMAN (1-733): 3.71e-62: 224: 69.50		ACTB_HUMAN (4-377): 0: 599: 94.12
+	Hs
		496806 TAU_HUMAN (1-733): 3.71e-62: 224: 69.50		ACTG_HUMAN (4-377): 0: 599: 94.39
+	Hs
		496813 TAU_HUMAN (1-733): 3.71e-62: 224: 69.50		ACTC_HUMAN (1-377): 0: 599: 100.00
+	Hs
		496816 TAU_HUMAN (1-733): 3.71e-62: 224: 69.50		ACTS_HUMAN (1-377): 0: 599: 98.94
+	Hs
		496759 TAU_HUMAN (1-733): 3.71e-62: 224: 69.50		ACTA_HUMAN (1-377): 0: 596: 98.41
+	Hs
		554290 MUC1_HUMAN (53-730): 8.07e-34: 141: 11.48		ACTA_HUMAN (1-377): 0: 596: 98.41
+	Hs
		503276 MTAP2_HUMAN (15-733): 2.73e-32: 137: 24.15		ACTB_HUMAN (4-377): 0: 599: 94.12
+	Hs
		932156 MDC1_HUMAN (2-721): 9.17e-27: 119: 9.02		ACTC_HUMAN (1-377): 0: 599: 100.00
+	Hs
		891699 ANK2_HUMAN (120-695): 5.01e-25: 114: 17.10		ACTB_HUMAN (4-377): 0: 599: 94.12
+	Ce
		109402 H2KY94_CAEEL (420-663): 6.69e-26: 109: 29.46		ACT4_CAEEL (1-377): 0: 601: 94.43
+	Hs
		930079 ANK2_HUMAN (120-695): 5.01e-25: 114: 17.10		ACTH_HUMAN (4-377): 0: 591: 98.93
+	Ce
		501479 Q95QG4_CAEEL (258-668): 2.84e-22: 102: 21.86		ACT4_CAEEL (1-377): 0: 601: 94.43
+	Ce
		137705 O02592_CAEEL (402-649): 3.4e-13: 74.5: 23.59		ACT4_CAEEL (1-377): 0: 601: 94.43
+	Hs
		203220 SYNJ1_HUMAN (336-712): 5.99e-10: 65: 13.02		ACTC_HUMAN (1-377): 0: 599: 100.00
+	Dm
		501445 CPN_DROME (322-731): 5.54e-09: 61.6: 13.08		ACT5_DROME (1-377): 0: 598: 93.10