HitPredict

Interactor 1: TAU (P10637)
Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau)
Gene: Mapt

Interactor 2: AP2M1 (P84091)
AP-2 complex subunit mu (AP-2 mu chain) (Adaptor protein complex AP-2 subunit mu) (Adaptor-related protein complex 2 subunit mu) (Clathrin assembly protein complex 2 mu medium chain) (Clathrin coat assembly protein AP50) (Clathrin coat-associated protein AP50) (Mu2-adaptin) (Plasma membrane adaptor AP-2 50 kDa protein)
Gene: AP2M1

Species: Mus musculus

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	30068389
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0009898 - cytoplasmic side of plasma membrane
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 733 Mm			1 435
+	Rn
		581982 TAU_RAT (1-733): 1.67e-78: 268: 88.46		AP2M1_RAT (1-435): 1.03e-178: 507: 100.00
+	Rn
		94205 F1LST4_RAT (1-732): 4.29e-78: 268: 88.58		AP2M1_RAT (1-435): 1.03e-178: 507: 100.00
+	Hs
		497422 TAU_HUMAN (1-733): 3.71e-62: 224: 69.50		AP2M1_HUMAN (1-435): 1.03e-178: 507: 100.00
+	Hs
		497548 TAU_HUMAN (1-733): 3.71e-62: 224: 69.50		AP1M1_HUMAN (2-434): 5.69e-170: 484: 38.85
+	Hs
		497844 TAU_HUMAN (1-733): 3.71e-62: 224: 69.50		AP3M1_HUMAN (1-434): 1.4e-123: 366: 24.66
+	Hs
		496626 TAU_HUMAN (1-733): 3.71e-62: 224: 69.50		AP3M2_HUMAN (1-434): 2.92e-119: 355: 24.89
+	Hs
		654028 MAP4_HUMAN (1-718): 9.04e-11: 67.7: 9.49		AP2M1_HUMAN (1-435): 1.03e-178: 507: 100.00
+	Hs
		203244 SYNJ1_HUMAN (336-712): 5.99e-10: 65: 13.02		AP2M1_HUMAN (1-435): 1.03e-178: 507: 100.00
+	Dm
		248311 Q9VLS7_DROME (23-733): 1.82e-11: 70.1: 10.76		O62530_DROME (1-435): 7.78e-171: 487: 86.56