HitPredict

Interactor 1: TAU (P10637)
Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau)
Gene: Mapt

Interactor 2: RHOG (P84096)
Rho-related GTP-binding protein RhoG (Sid 10750)
Gene: RHOG

Species: Mus musculus

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	30068389
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0019901 - protein kinase binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 733 Mm			1 191
+	Mm
		498148 TAU_MOUSE (1-733): 4.79e-86: 288: 100.00		RHOA_MOUSE (5-191): 4.18e-79: 235: 55.62
+	Hs
		496789 TAU_HUMAN (1-733): 3.71e-62: 224: 69.50		RAC1_HUMAN (1-191): 3.6e-82: 243: 71.88
+	Hs
		496691 TAU_HUMAN (1-733): 3.71e-62: 224: 69.50		CDC42_HUMAN (1-191): 1.3e-78: 234: 60.73
+	Hs
		496717 TAU_HUMAN (1-733): 3.71e-62: 224: 69.50		RHOA_HUMAN (5-191): 1.26e-78: 234: 55.62
+	Hs
		436133 TAU_HUMAN (1-733): 3.71e-62: 224: 69.50		RHOC_HUMAN (5-191): 8.34e-77: 230: 56.15
+	Hs
		496684 TAU_HUMAN (1-733): 3.71e-62: 224: 69.50		RAC3_HUMAN (1-177): 1.67e-75: 226: 72.88
+	Hs
		925204 ANK2_HUMAN (120-695): 5.01e-25: 114: 17.10		RAC1_HUMAN (1-191): 3.6e-82: 243: 71.88
+	Hs
		297823 K0754_HUMAN (244-730): 1.07e-19: 97: 8.42		RAC1_HUMAN (1-191): 3.6e-82: 243: 71.88
+	Hs
		297827 K0754_HUMAN (244-730): 1.07e-19: 97: 8.42		RHOG_HUMAN (1-191): 9.12e-82: 242: 100.00
+	Ce
		136793 UNC89_CAEEL (364-731): 2.36e-16: 86.2: 13.21		RAC1_CAEEL (1-191): 4.3e-83: 245: 66.49
+	Hs
		297812 K0754_HUMAN (244-730): 1.07e-19: 97: 8.42		RAC2_HUMAN (1-191): 1.28e-78: 234: 71.35
+	Hs
		297820 K0754_HUMAN (244-730): 1.07e-19: 97: 8.42		RHOA_HUMAN (5-191): 1.26e-78: 234: 55.62
+	Hs
		297809 K0754_HUMAN (244-730): 1.07e-19: 97: 8.42		RHOC_HUMAN (5-191): 8.34e-77: 230: 56.15
+	Hs
		297819 K0754_HUMAN (244-730): 1.07e-19: 97: 8.42		RAC3_HUMAN (1-177): 1.67e-75: 226: 72.88
+	Ce
		104464 UNC89_CAEEL (364-731): 2.36e-16: 86.2: 13.21		G5EBV3_CAEEL (2-191): 3.88e-79: 235: 60.00
+	Ce
		136794 UNC89_CAEEL (364-731): 2.36e-16: 86.2: 13.21		CDC42_CAEEL (1-191): 1.77e-76: 228: 58.12
+	Ce
		136800 UNC89_CAEEL (364-731): 2.36e-16: 86.2: 13.21		RHO1_CAEEL (5-191): 3.39e-75: 225: 56.68
+	Hs
		653946 MAP4_HUMAN (1-718): 9.04e-11: 67.7: 9.49		CDC42_HUMAN (1-191): 1.3e-78: 234: 60.73
+	Hs
		894572 MUC12_HUMAN (164-729): 2.77e-10: 66.5: 11.60		CDC42_HUMAN (1-191): 1.3e-78: 234: 60.73
+	Hs
		564677 TARA_HUMAN (7-691): 9.27e-09: 61.2: 9.57		RHOQ_HUMAN (4-189): 5.74e-73: 220: 56.84