HitPredict

Interactor 1: ACRZ (P0AAW9)
Multidrug efflux pump accessory protein AcrZ (AcrAB-TolC multidrug efflux pump accessory protein AcrZ) (Acridine resistance protein Z)
Gene: ACRZ

Interactor 2: ACRB (P31224)
Multidrug efflux pump subunit AcrB (AcrAB-TolC multidrug efflux pump subunit AcrB) (Acridine resistance protein B)
Gene: ACRB

Species: Escherichia coli K-12

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.69	0.90	0.788

Property	Details
Experiments	24747401, 23010927
Identification Methods	molecular sieving, pull down, x-ray crystallography, adenylate cyclase complementation
Interaction Type	direct interaction, physical association, association

Property	Details
Interacting Pfam domains	ACR_tran~AcrZ
Common GO terms	GO:0005886 - plasma membrane GO:0042910 - xenobiotic transmembrane transporter activity GO:0046677 - response to antibiotic
Homologous interactions	0