HitPredict

Interactor 1: TAU (P10637)
Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau)
Gene: Mapt

Interactor 2: HS105 (Q61699)
Heat shock protein 105 kDa (42 degrees C-HSP) (Heat shock 110 kDa protein) (Heat shock-related 100 kDa protein E7I) (HSP-E7I)
Gene: Hsph1

Species: Mus musculus

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	30068389
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005576 - extracellular region GO:0005634 - nucleus GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 733 Mm			1 858
+	Mm
		497946 TAU_MOUSE (1-733): 4.79e-86: 288: 100.00		HS74L_MOUSE (1-856): 0: 919: 55.96
+	Hs
		497367 TAU_HUMAN (1-733): 3.71e-62: 224: 69.50		HS105_HUMAN (1-858): 0: 954: 92.55
+	Mm
		498021 TAU_MOUSE (1-733): 4.79e-86: 288: 100.00		Q3U2G2_MOUSE (1-858): 0: 873: 60.26
+	Hs
		320800 TAU_HUMAN (1-733): 3.71e-62: 224: 69.50		HS74L_HUMAN (1-856): 0: 920: 56.66
+	Rn
		291980 TAU_RAT (1-733): 1.67e-78: 268: 88.46		HSP74_RAT (1-858): 0: 873: 59.91
+	Rn
		94108 F1LST4_RAT (1-732): 4.29e-78: 268: 88.58		HSP74_RAT (1-858): 0: 873: 59.91
+	Hs
		496426 TAU_HUMAN (1-733): 3.71e-62: 224: 69.50		HSP74_HUMAN (1-858): 0: 863: 60.61
+	Hs
		554275 MUC1_HUMAN (53-730): 8.07e-34: 141: 11.48		HSP74_HUMAN (1-858): 0: 863: 60.61
+	Dm
		1370298 Q9VLS7_DROME (23-733): 1.82e-11: 70.1: 10.76		Q9VUC1_DROME (1-856): 0: 821: 41.61
+	Hs
		497878 TAU_HUMAN (1-733): 3.71e-62: 224: 69.50		HYOU1_HUMAN (1-807): 1.68e-80: 281: 27.67
+	Mm
		497918 TAU_MOUSE (1-733): 4.79e-86: 288: 100.00		HS71L_MOUSE (600-717): 2.4e-33: 139: 19.33
+	Mm
		497989 TAU_MOUSE (1-733): 4.79e-86: 288: 100.00		HSP7C_MOUSE (600-710): 9.2e-33: 137: 16.07
+	Mm
		498048 TAU_MOUSE (1-733): 4.79e-86: 288: 100.00		HS71A_MOUSE (600-708): 1.26e-30: 130: 19.09
+	Hs
		496165 TAU_HUMAN (1-733): 3.71e-62: 224: 69.50		HSP7C_HUMAN (600-710): 5e-33: 138: 16.07
+	Hs
		496425 TAU_HUMAN (1-733): 3.71e-62: 224: 69.50		HS71L_HUMAN (588-718): 6.38e-33: 137: 18.80
+	Hs
		483743 TAU_HUMAN (1-733): 3.71e-62: 224: 69.50		HS71A_HUMAN (600-708): 2.3e-32: 135: 20.91
+	Hs
		496242 TAU_HUMAN (1-733): 3.71e-62: 224: 69.50		HSP76_HUMAN (600-727): 5.26e-28: 122: 20.16
+	Hs
		503916 ANK2_HUMAN (120-695): 5.01e-25: 114: 17.10		HSP7C_HUMAN (600-710): 5e-33: 138: 16.07
+	Hs
		483759 ANK2_HUMAN (120-695): 5.01e-25: 114: 17.10		HS71A_HUMAN (600-708): 2.3e-32: 135: 20.91
+	Hs
		503487 MAP4_HUMAN (1-718): 9.04e-11: 67.7: 9.49		HSP7C_HUMAN (600-710): 5e-33: 138: 16.07