HitPredict

Interactor 1: TAU (P10637)
Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau)
Gene: Mapt

Interactor 2: SRSF2 (Q62093)
Serine/arginine-rich splicing factor 2 (Protein PR264) (Putative myelin regulatory factor 1) (MRF-1) (Splicing component, 35 kDa) (Splicing factor SC35) (SC-35) (Splicing factor, arginine/serine-rich 2)
Gene: SRSF2

Species: Mus musculus

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	30068389
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 733 Mm			1 221
+	Mm
		498054 TAU_MOUSE (1-733): 4.79e-86: 288: 100.00		Q62029_MOUSE (6-202): 3.9e-39: 143: 18.27
+	Rn
		582032 TAU_RAT (1-733): 1.67e-78: 268: 88.46		PABP1_RAT (6-202): 1.95e-41: 150: 18.27
+	Rn
		94258 F1LST4_RAT (1-732): 4.29e-78: 268: 88.58		PABP1_RAT (6-202): 1.95e-41: 150: 18.27
+	Hs
		497073 TAU_HUMAN (1-733): 3.71e-62: 224: 69.50		SF3B4_HUMAN (4-205): 1.41e-52: 176: 17.24
+	Hs
		496179 TAU_HUMAN (1-733): 3.71e-62: 224: 69.50		PABP1_HUMAN (6-202): 1.69e-41: 150: 18.27
+	Hs
		496868 TAU_HUMAN (1-733): 3.71e-62: 224: 69.50		SRSF2_HUMAN (1-221): 1.22e-43: 147: 100.00
+	Rn
		582044 TAU_RAT (1-733): 1.67e-78: 268: 88.46		PUF60_RAT (8-108): 1.35e-23: 100: 23.76
+	Mm
		497953 TAU_MOUSE (1-733): 4.79e-86: 288: 100.00		TIA1_MOUSE (7-184): 8.63e-17: 79.6: 11.67
+	Hs
		496937 TAU_HUMAN (1-733): 3.71e-62: 224: 69.50		ELAV2_HUMAN (1-195): 6.01e-38: 136: 15.79
+	Hs
		496957 TAU_HUMAN (1-733): 3.71e-62: 224: 69.50		PABP4_HUMAN (5-191): 4.16e-25: 104: 13.37
+	Hs
		497752 TAU_HUMAN (1-733): 3.71e-62: 224: 69.50		PUF60_HUMAN (8-108): 1.34e-23: 100: 23.76
+	Hs
		496405 TAU_HUMAN (1-733): 3.71e-62: 224: 69.50		TIA1_HUMAN (9-184): 2.34e-16: 78.5: 10.67
+	Hs
		497020 TAU_HUMAN (1-733): 3.71e-62: 224: 69.50		ELAV3_HUMAN (115-195): 1.55e-11: 64.6: 11.11
+	Hs
		516595 KMT2C_HUMAN (10-696): 1.37e-11: 70.4: 9.61		PABP1_HUMAN (6-202): 1.69e-41: 150: 18.27
+	Hs
		965152 ANK2_HUMAN (120-695): 5.01e-25: 114: 17.10		PABP3_HUMAN (15-221): 2.48e-24: 101: 16.91