HitPredict

Interactor 1: TAU (P10637)
Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau)
Gene: Mapt

Interactor 2: ACTY (Q8R5C5)
Beta-centractin (Actin-related protein 1B) (ARP1B)
Gene: Actr1b

Species: Mus musculus

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	30068389
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 733 Mm			1 376
+	Mm
		497963 TAU_MOUSE (1-733): 4.79e-86: 288: 100.00		ACTZ_MOUSE (1-376): 0: 731: 91.22
+	Rn
		581983 TAU_RAT (1-733): 1.67e-78: 268: 88.46		ACTZ_RAT (1-376): 0: 731: 91.22
+	Rn
		94206 F1LST4_RAT (1-732): 4.29e-78: 268: 88.58		ACTZ_RAT (1-376): 0: 731: 91.22
+	Hs
		496493 TAU_HUMAN (1-733): 3.71e-62: 224: 69.50		ACTY_HUMAN (1-376): 0: 772: 98.94
+	Hs
		496704 TAU_HUMAN (1-733): 3.71e-62: 224: 69.50		ACTZ_HUMAN (1-376): 0: 731: 91.22
+	Mm
		498001 TAU_MOUSE (1-733): 4.79e-86: 288: 100.00		ACTC_MOUSE (5-376): 0: 572: 53.46
+	Hs
		496683 TAU_HUMAN (1-733): 3.71e-62: 224: 69.50		ACTB_HUMAN (8-376): 0: 576: 53.35
+	Hs
		496806 TAU_HUMAN (1-733): 3.71e-62: 224: 69.50		ACTG_HUMAN (7-376): 0: 576: 53.48
+	Hs
		496759 TAU_HUMAN (1-733): 3.71e-62: 224: 69.50		ACTA_HUMAN (5-376): 0: 572: 53.19
+	Hs
		496813 TAU_HUMAN (1-733): 3.71e-62: 224: 69.50		ACTC_HUMAN (5-376): 0: 572: 53.46
+	Hs
		496816 TAU_HUMAN (1-733): 3.71e-62: 224: 69.50		ACTS_HUMAN (5-376): 0: 571: 52.93
+	Hs
		503276 MTAP2_HUMAN (15-733): 2.73e-32: 137: 24.15		ACTB_HUMAN (8-376): 0: 576: 53.35
+	Hs
		554290 MUC1_HUMAN (53-730): 8.07e-34: 141: 11.48		ACTA_HUMAN (5-376): 0: 572: 53.19
+	Hs
		932156 MDC1_HUMAN (2-721): 9.17e-27: 119: 9.02		ACTC_HUMAN (5-376): 0: 572: 53.46
+	Hs
		891699 ANK2_HUMAN (120-695): 5.01e-25: 114: 17.10		ACTB_HUMAN (8-376): 0: 576: 53.35
+	Ce
		109402 H2KY94_CAEEL (420-663): 6.69e-26: 109: 29.46		ACT4_CAEEL (8-376): 0: 576: 54.16
+	Hs
		930079 ANK2_HUMAN (120-695): 5.01e-25: 114: 17.10		ACTH_HUMAN (7-376): 0: 569: 53.48
+	Ce
		501479 Q95QG4_CAEEL (258-668): 2.84e-22: 102: 21.86		ACT4_CAEEL (8-376): 0: 576: 54.16
+	Ce
		137705 O02592_CAEEL (402-649): 3.4e-13: 74.5: 23.59		ACT4_CAEEL (8-376): 0: 576: 54.16
+	Hs
		203220 SYNJ1_HUMAN (336-712): 5.99e-10: 65: 13.02		ACTC_HUMAN (5-376): 0: 572: 53.46