HitPredict

Interactor 1: TAU (P10637)
Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau)
Gene: Mapt

Interactor 2: 1433B (Q9CQV8)
14-3-3 protein beta/alpha (Protein kinase C inhibitor protein 1) (KCIP-1) [Cleaved into: 14-3-3 protein beta/alpha, N-terminally processed]
Gene: Ywhab

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	19014373, 30068389
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0044877 - protein-containing complex binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 733 Mm			1 246
+	Mm
		497973 TAU_MOUSE (1-733): 4.79e-86: 288: 100.00		1433E_MOUSE (3-243): 1.26e-143: 403: 65.02
+	Mm
		497995 TAU_MOUSE (1-733): 4.79e-86: 288: 100.00		1433Z_MOUSE (3-244): 6.05e-142: 398: 86.78
+	Rn
		581965 TAU_RAT (1-733): 1.67e-78: 268: 88.46		1433E_RAT (3-243): 1.26e-143: 403: 65.02
+	Rn
		94188 F1LST4_RAT (1-732): 4.29e-78: 268: 88.58		1433E_RAT (3-243): 1.26e-143: 403: 65.02
+	Rn
		581974 TAU_RAT (1-733): 1.67e-78: 268: 88.46		1433Z_RAT (3-244): 6.05e-142: 398: 86.78
+	Rn
		94197 F1LST4_RAT (1-732): 4.29e-78: 268: 88.58		1433Z_RAT (3-244): 6.05e-142: 398: 86.78
+	Hs
		496415 TAU_HUMAN (1-733): 3.71e-62: 224: 69.50		1433B_HUMAN (1-246): 5.21e-144: 404: 98.78
+	Hs
		496737 TAU_HUMAN (1-733): 3.71e-62: 224: 69.50		1433E_HUMAN (3-243): 1.26e-143: 403: 65.02
+	Hs
		496795 TAU_HUMAN (1-733): 3.71e-62: 224: 69.50		1433Z_HUMAN (3-244): 2.35e-141: 397: 87.19
+	Rn
		581977 TAU_RAT (1-733): 1.67e-78: 268: 88.46		1433T_RAT (3-244): 1.02e-123: 353: 80.99
+	Rn
		94200 F1LST4_RAT (1-732): 4.29e-78: 268: 88.58		1433T_RAT (3-244): 1.02e-123: 353: 80.99
+	Mm
		497971 TAU_MOUSE (1-733): 4.79e-86: 288: 100.00		1433G_MOUSE (3-246): 8.54e-109: 315: 75.81
+	Mm
		498003 TAU_MOUSE (1-733): 4.79e-86: 288: 100.00		1433F_MOUSE (4-244): 4.83e-107: 310: 75.92
+	Rn
		581964 TAU_RAT (1-733): 1.67e-78: 268: 88.46		1433G_RAT (3-246): 8.54e-109: 315: 75.81
+	Rn
		94187 F1LST4_RAT (1-732): 4.29e-78: 268: 88.58		1433G_RAT (3-246): 8.54e-109: 315: 75.81
+	Hs
		496356 TAU_HUMAN (1-733): 3.71e-62: 224: 69.50		1433T_HUMAN (3-244): 2.85e-124: 354: 80.99
+	Mm
		250865 TAU_MOUSE (1-733): 4.79e-86: 288: 100.00		1433S_MOUSE (3-234): 1.45e-96: 284: 68.38
+	Hs
		496727 TAU_HUMAN (1-733): 3.71e-62: 224: 69.50		1433G_HUMAN (3-246): 8.54e-109: 315: 75.81
+	Hs
		496898 TAU_HUMAN (1-733): 3.71e-62: 224: 69.50		1433F_HUMAN (4-244): 9.94e-107: 310: 75.92
+	Hs
		496416 TAU_HUMAN (1-733): 3.71e-62: 224: 69.50		1433S_HUMAN (3-239): 3.7e-99: 290: 68.62