HitPredict

Interactor 1: TAU (P10637)
Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau)
Gene: Mapt

Interactor 2: AP3S1 (Q9DCR2)
AP-3 complex subunit sigma-1 (AP-3 complex subunit sigma-3A) (Adaptor-related protein complex 3 subunit sigma-1) (Sigma-3A-adaptin) (Sigma3A-adaptin) (Sigma-adaptin 3a)
Gene: AP3S1

Species: Mus musculus

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	30068389
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0046907 - intracellular transport
Homologous interactions	14

Homologous interactions

Color coding for hit scores

	1 733 Mm			1 193
+	Hs
		497365 TAU_HUMAN (1-733): 3.71e-62: 224: 69.50		AP3S1_HUMAN (1-193): 7.1e-75: 224: 100.00
+	Mm
		498008 TAU_MOUSE (1-733): 4.79e-86: 288: 100.00		AP2M1_MOUSE (1-186): 6.1e-47: 160: 11.83
+	Rn
		581982 TAU_RAT (1-733): 1.67e-78: 268: 88.46		AP2M1_RAT (1-186): 6.1e-47: 160: 11.83
+	Rn
		94205 F1LST4_RAT (1-732): 4.29e-78: 268: 88.58		AP2M1_RAT (1-186): 6.1e-47: 160: 11.83
+	Hs
		496667 TAU_HUMAN (1-733): 3.71e-62: 224: 69.50		AP1S2_HUMAN (2-158): 5.07e-50: 160: 35.03
+	Hs
		497422 TAU_HUMAN (1-733): 3.71e-62: 224: 69.50		AP2M1_HUMAN (1-186): 6.1e-47: 160: 11.83
+	Hs
		497844 TAU_HUMAN (1-733): 3.71e-62: 224: 69.50		AP3M1_HUMAN (1-188): 1.37e-44: 154: 18.09
+	Hs
		496722 TAU_HUMAN (1-733): 3.71e-62: 224: 69.50		COPZ1_HUMAN (2-166): 7.56e-45: 148: 22.02
+	Hs
		496627 TAU_HUMAN (1-733): 3.71e-62: 224: 69.50		AP2S1_HUMAN (1-148): 1.73e-43: 143: 40.54
+	Mm
		592762 MTAP2_MOUSE (21-733): 1.11e-34: 144: 24.55		AP2S1_MOUSE (1-148): 1.73e-43: 143: 40.54
+	Hs
		654028 MAP4_HUMAN (1-718): 9.04e-11: 67.7: 9.49		AP2M1_HUMAN (1-186): 6.1e-47: 160: 11.83
+	Dm
		248311 Q9VLS7_DROME (23-733): 1.82e-11: 70.1: 10.76		O62530_DROME (1-186): 9.01e-46: 157: 13.98
+	Hs
		203244 SYNJ1_HUMAN (336-712): 5.99e-10: 65: 13.02		AP2M1_HUMAN (1-186): 6.1e-47: 160: 11.83
+	Mm
		649203 MAP4_MOUSE (26-724): 1.54e-10: 66.9: 10.81		AP2S1_MOUSE (1-148): 1.73e-43: 143: 40.54