Interactor 1: KAP0 (P10644)
cAMP-dependent protein kinase type I-alpha regulatory subunit (Tissue-specific extinguisher 1) (TSE1)
Gene: PRKAR1A
Interactor 2: KAP1 (P31321)
cAMP-dependent protein kinase type I-beta regulatory subunit
Gene: PRKAR1B
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.95 | 1.00 | 0.975 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 12634056, 33961781, 26186194, 28514442, 32296183, 31980649, 8407966, 35235311, unassigned1304, unassigned2173 |
| Identification Methods | two hybrid, affinity chromatography technology, pull down, cross-linking study, anti tag coimmunoprecipitation, two hybrid prey pooling approach, two hybrid array, validated two hybrid |
| Interaction Type | direct interaction, physical association, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | cNMP_binding~cNMP_binding, RIIa~RIIa |
| Common GO terms | GO:0004862 - cAMP-dependent protein kinase inhibitor activity GO:0005771 - multivesicular body GO:0005829 - cytosol GO:0005952 - cAMP-dependent protein kinase complex GO:0008603 - cAMP-dependent protein kinase regulator activity and 5 others more... |
| Homologous interactions | 17 |
Homologous interactions
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
