Interactor 1: KAP0 (P10644)
cAMP-dependent protein kinase type I-alpha regulatory subunit (Tissue-specific extinguisher 1) (TSE1)
Gene: PRKAR1A

Interactor 2: MK07 (Q13164)
Mitogen-activated protein kinase 7 (MAP kinase 7) (MAPK 7) (EC 2.7.11.24) (Big MAP kinase 1) (BMK-1) (Extracellular signal-regulated kinase 5) (ERK-5)
Gene: MAPK7

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.54 1.00 0.737

The method score is based on:

Property Details
Experiments 31980649, unassigned2173
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains Pkinase~cNMP_binding, Pkinase~RIIa
Common GO terms GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0007189 - adenylate cyclase-activating G protein-coupled receptor signaling pathway
GO:0035556 - intracellular signal transduction
Homologous interactions 5

Homologous interactions

Color coding for hit scores

1 381
Hs

1 816
+ Rn
+ Hs
+ Rn
+ Rn
+ Rn

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024