Interactor 1: METK1 (P10659)
S-adenosylmethionine synthase 1 (AdoMet synthase 1) (EC 2.5.1.6) (Methionine adenosyltransferase 1) (MAT 1)
Gene: SAM1

Interactor 2: METK1 (P10659)
S-adenosylmethionine synthase 1 (AdoMet synthase 1) (EC 2.5.1.6) (Methionine adenosyltransferase 1) (MAT 1)
Gene: SAM1

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.58 1.00 0.762

The method score is based on:

Property Details
Experiments 18719252, unassigned1933
Identification Methods two hybrid, dihydrofolate reductase reconstruction
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains S-AdoMet_synt_C~S-AdoMet_synt_C, S-AdoMet_synt_C~S-AdoMet_synt_M, S-AdoMet_synt_C~S-AdoMet_synt_N, S-AdoMet_synt_M~S-AdoMet_synt_M, S-AdoMet_synt_M~S-AdoMet_synt_N, S-AdoMet_synt_N~S-AdoMet_synt_N
Common GO terms GO:0004478 - methionine adenosyltransferase activity
GO:0005524 - ATP binding
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0006555 - methionine metabolic process
and 4 others

more...

Homologous interactions 15

Homologous interactions

Color coding for hit scores

1 382
Sc

1 382
+ Hs
+ Hs
+ Hs
+ Rn
+ Sc
+ Sp
+ Sc
+ Zm
+ Ce
+ Ce
+ Ce
+ Ce
+ Dm
+ Ec
+ Pf

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Last updated: 15 Jul 2024