Interactor 1: METK1 (P10659)
S-adenosylmethionine synthase 1 (AdoMet synthase 1) (EC 2.5.1.6) (Methionine adenosyltransferase 1) (MAT 1)
Gene: SAM1
Interactor 2: METK2 (P19358)
S-adenosylmethionine synthase 2 (AdoMet synthase 2) (EC 2.5.1.6) (Methionine adenosyltransferase 2) (MAT 2)
Gene: SAM2
Species: Saccharomyces cerevisiae S288C
Source: mint
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.89 | 1.00 | 0.944 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 16429126, 26527276, 16554755, 18719252, 37968396, unassigned1933 |
| Identification Methods | affinity chromatography technology, two hybrid, tandem affinity purification, dihydrofolate reductase reconstruction |
| Interaction Type | physical association, direct interaction, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | S-AdoMet_synt_C~S-AdoMet_synt_C, S-AdoMet_synt_C~S-AdoMet_synt_M, S-AdoMet_synt_C~S-AdoMet_synt_N, S-AdoMet_synt_M~S-AdoMet_synt_M, S-AdoMet_synt_M~S-AdoMet_synt_N, S-AdoMet_synt_N~S-AdoMet_synt_N |
| Common GO terms | GO:0004478 - methionine adenosyltransferase activity GO:0005524 - ATP binding GO:0005829 - cytosol GO:0006555 - methionine metabolic process GO:0006556 - S-adenosylmethionine biosynthetic process and 3 others more... |
| Homologous interactions | 16 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
