HitPredict

Interactor 1: METK1 (P10659)
S-adenosylmethionine synthase 1 (AdoMet synthase 1) (EC 2.5.1.6) (Methionine adenosyltransferase 1) (MAT 1)
Gene: SAM1

Interactor 2: HSP79 (P32590)
Heat shock protein homolog SSE2
Gene: SSE2

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	19536198
Identification Methods	tandem affinity purification
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 382 Sc			1 693
+	Sc
		583209 METK2_YEAST (2-382): 0: 654: 92.13		HSP79_YEAST (1-693): 0: 1325: 100.00
+	Sc
		498477 METK1_YEAST (1-382): 0: 660: 100.00		HSP7F_YEAST (1-693): 0: 1007: 75.61
+	Sc
		583208 METK2_YEAST (2-382): 0: 654: 92.13		HSP7F_YEAST (1-693): 0: 1007: 75.61
+	Hs
		503524 METK2_HUMAN (3-382): 0: 666: 68.16		HSP7C_HUMAN (2-645): 0: 851: 26.92
+	Hs
		678589 METK2_HUMAN (3-382): 0: 666: 68.16		HSP74_HUMAN (6-650): 2.75e-140: 432: 38.18
+	Sc
		449900 METK2_YEAST (2-382): 0: 654: 92.13		HSP73_YEAST (1-642): 1.34e-73: 252: 28.55
+	Sc
		493014 METK1_YEAST (1-382): 0: 660: 100.00		HSP72_YEAST (1-429): 1.15e-71: 246: 34.95
+	Sc
		498439 METK1_YEAST (1-382): 0: 660: 100.00		HSP74_YEAST (1-642): 3.15e-71: 245: 27.93
+	Sc
		490124 METK1_YEAST (1-382): 0: 660: 100.00		HSP71_YEAST (1-429): 5.26e-71: 244: 34.72
+	Sc
		493158 METK2_YEAST (2-382): 0: 654: 92.13		HSP72_YEAST (1-429): 1.15e-71: 246: 34.95
+	Sc
		490287 METK2_YEAST (2-382): 0: 654: 92.13		HSP71_YEAST (1-429): 5.26e-71: 244: 34.72