HitPredict

Interactor 1: RL4A (P10664)
Large ribosomal subunit protein uL4A (60S ribosomal protein L4-A) (L2) (RP2) (YL2)
Gene: RPL4A

Interactor 2: MAK5 (P38112)
ATP-dependent RNA helicase MAK5 (EC 3.6.4.13) (Maintenance of killer protein 5)
Gene: MAK5

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	16429126, 30568249
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 362 Sc			1 773
+	Hs
		133906 RL4_HUMAN (2-339): 3.59e-177: 500: 59.29		DDX3X_HUMAN (28-618): 9.99e-129: 400: 20.92
+	Sc
		498801 RL4A_YEAST (1-362): 0: 515: 100.00		DBP2_YEAST (62-611): 3.49e-122: 379: 21.62
+	Hs
		736716 RL4_HUMAN (2-339): 3.59e-177: 500: 59.29		DDX24_HUMAN (242-734): 2.14e-67: 241: 33.13
+	Sc
		499056 RL4A_YEAST (1-362): 0: 515: 100.00		HAS1_YEAST (178-598): 2.55e-41: 160: 31.46
+	Sc
		829682 RL4B_YEAST (1-362): 0: 515: 99.72		HAS1_YEAST (178-598): 2.55e-41: 160: 31.46
+	Sc
		498912 RL4A_YEAST (1-362): 0: 515: 100.00		DBP8_YEAST (178-619): 1.57e-39: 153: 29.33
+	Hs
		736647 RL4_HUMAN (2-339): 3.59e-177: 500: 59.29		DDX27_HUMAN (57-587): 1.9e-39: 158: 28.55
+	Hs
		736765 RL4_HUMAN (2-339): 3.59e-177: 500: 59.29		DDX18_HUMAN (70-598): 3.25e-38: 153: 29.16