Interactor 1: DNAB (P0ACB0)
Replicative DNA helicase DnaB (EC 5.6.2.3) (DNA 5'-3' helicase DnaB)
Gene: DNAB
Interactor 2: DNAC (P0AEF0)
Replicative helicase loader DnaC (EC 3.6.4.-) (DNA replication protein DnaC)
Gene: DNAC
Species: Escherichia coli K-12
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.96 | 0.90 | 0.932 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 24561554, 14715083, 9562559, 12767828, 11031115, 8106460, 11250911, 11333269, 1093174, 15690043, 20129058, 23562643 |
| Identification Methods | two hybrid, biochemical, 3D electron microscopy, biophysical, electron microscopy, coimmunoprecipitation, experimental interaction detection, molecular sieving, cosedimentation in solution, ion exchange chromatography and 5 others
more... |
| Interaction Type | direct interaction, association, physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | DnaB_C~IstB_IS21 |
| Common GO terms | GO:0003677 - DNA binding GO:0005524 - ATP binding GO:0006260 - DNA replication GO:0006269 - DNA replication, synthesis of primer GO:0006270 - DNA replication initiation and 7 others more... |
| Homologous interactions | 0 |
Service provided by Combinatics, Japan
Last updated: 11Aug2025
