Interactor 1: PLCG1 (P10686)
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 (EC 3.1.4.11) (Phosphoinositide phospholipase C-gamma-1) (Phospholipase C-gamma-1) (PLC-gamma-1)
Gene: PLCG1

Interactor 2: NCAM1 (P13596)
Neural cell adhesion molecule 1 (N-CAM-1) (NCAM-1) (CD antigen CD56)
Gene: NCAM1

Species: Rattus norvegicus

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.52 1.00 0.724

The method score is based on:

Property Details
Experiments 15865439
Identification Methods affinity chromatography technology, pull down
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains SH2~fn3
Common GO terms GO:0005886 - plasma membrane
GO:0005911 - cell-cell junction
GO:0019722 - calcium-mediated signaling
GO:0050804 - modulation of chemical synaptic transmission
GO:0098685 - Schaffer collateral - CA1 synapse
and 1 others

more...

Homologous interactions 3

Homologous interactions

Color coding for hit scores

1 1290
Rn

1 858
+ Mm
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024