HitPredict

Interactor 1: KIT (P10721)
Mast/stem cell growth factor receptor Kit (SCFR) (EC 2.7.10.1) (Piebald trait protein) (PBT) (Proto-oncogene c-Kit) (Tyrosine-protein kinase Kit) (p145 c-kit) (v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog) (CD antigen CD117)
Gene: KIT

Interactor 2: ENPL (P14625)
Endoplasmin (94 kDa glucose-regulated protein) (GRP-94) (Heat shock protein 90 kDa beta member 1) (Heat shock protein family C member 4) (Tumor rejection antigen 1) (gp96 homolog)
Gene: HSP90B1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	25737303
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 976 Hs			1 803
+	Hs
		437821 PGFRB_HUMAN (30-954): 0: 591: 30.62		HS90B_HUMAN (75-783): 0: 997: 46.54
+	Hs
		431450 PGFRB_HUMAN (30-954): 0: 591: 30.62		HS90A_HUMAN (60-783): 0: 990: 45.34
+	Hs
		431600 FLT3_HUMAN (11-968): 1.65e-171: 528: 29.98		HS90A_HUMAN (60-783): 0: 990: 45.34
+	Hs
		437897 FGFR3_HUMAN (3-331): 4.6e-51: 195: 13.39		HS90B_HUMAN (75-783): 0: 997: 46.54
+	Hs
		431536 FGFR3_HUMAN (3-331): 4.6e-51: 195: 13.39		HS90A_HUMAN (60-783): 0: 990: 45.34
+	Hs
		169160 MUSK_HUMAN (5-199): 7.9e-32: 136: 13.55		HS90B_HUMAN (75-783): 0: 997: 46.54
+	Hs
		169159 MUSK_HUMAN (5-199): 7.9e-32: 136: 13.55		HS90A_HUMAN (60-783): 0: 990: 45.34
+	Hs
		437895 FGFR4_HUMAN (4-224): 3.99e-23: 107: 13.21		HS90B_HUMAN (75-783): 0: 997: 46.54
+	Hs
		437838 FGFR1_HUMAN (4-235): 6.88e-22: 104: 13.25		HS90B_HUMAN (75-783): 0: 997: 46.54
+	Hs
		431534 FGFR4_HUMAN (4-224): 3.99e-23: 107: 13.21		HS90A_HUMAN (60-783): 0: 990: 45.34
+	Hs
		431472 FGFR1_HUMAN (4-235): 6.88e-22: 104: 13.25		HS90A_HUMAN (60-783): 0: 990: 45.34
+	Hs
		426977 CSF1R_HUMAN (209-511): 1.03e-12: 74.4: 14.10		HS90B_HUMAN (75-783): 0: 997: 46.54
+	Hs
		431596 VGFR2_HUMAN (3-106): 1.62e-13: 77.5: 14.04		HS90A_HUMAN (60-783): 0: 990: 45.34
+	Hs
		437949 VGFR3_HUMAN (3-111): 3.96e-11: 69.4: 13.93		HS90B_HUMAN (75-783): 0: 997: 46.54
+	Hs
		426974 CSF1R_HUMAN (209-511): 1.03e-12: 74.4: 14.10		HS90A_HUMAN (60-783): 0: 990: 45.34
+	Hs
		431595 VGFR3_HUMAN (3-111): 3.96e-11: 69.4: 13.93		HS90A_HUMAN (60-783): 0: 990: 45.34