HitPredict

Interactor 1: KNIR (P10734)
Zygotic gap protein knirps (Nuclear receptor subfamily 0 group A member 1)
Gene: kni

Interactor 2: UBX (P83949)
Homeotic protein ultrabithorax
Gene: UBX

Species: Drosophila melanogaster

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	25869471, 30247122
Identification Methods	protein complementation assay
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0006355 - regulation of DNA-templated transcription GO:0045892 - negative regulation of DNA-templated transcription
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 429 Dm			1 389
+	Dm
		499300 KNIR_DROME (1-429): 1.9e-173: 494: 100.00		ABDA_DROME (260-376): 4.98e-42: 157: 59.32
+	Dm
		558426 7UP1_DROME (2-306): 3.86e-76: 248: 23.44		UBX_DROME (1-389): 3.26e-124: 365: 100.00
+	Dm
		447313 KNIR_DROME (1-429): 1.9e-173: 494: 100.00		SCR_DROME (289-353): 5.65e-24: 104: 80.00
+	Dm
		548012 EGON_DROME (1-341): 2.09e-70: 228: 33.85		UBX_DROME (1-389): 3.26e-124: 365: 100.00
+	Dm
		949993 HR78_DROME (3-264): 1.1e-56: 198: 20.91		UBX_DROME (1-389): 3.26e-124: 365: 100.00
+	Dm
		680109 HR3_DROME (4-127): 4.18e-45: 164: 33.87		UBX_DROME (1-389): 3.26e-124: 365: 100.00
+	Dm
		558423 7UP1_DROME (2-306): 3.86e-76: 248: 23.44		ABDA_DROME (260-376): 4.98e-42: 157: 59.32
+	Dm
		548011 EGON_DROME (1-341): 2.09e-70: 228: 33.85		ABDA_DROME (260-376): 4.98e-42: 157: 59.32
+	Dm
		367172 7UP1_DROME (2-306): 3.86e-76: 248: 23.44		ANTP_DROME (161-375): 5.32e-31: 123: 32.56
+	Dm
		668246 HR78_DROME (3-264): 1.1e-56: 198: 20.91		ABDA_DROME (260-376): 4.98e-42: 157: 59.32
+	Dm
		367191 HR78_DROME (3-264): 1.1e-56: 198: 20.91		ANTP_DROME (161-375): 5.32e-31: 123: 32.56
+	Hs
		446867 RXRG_HUMAN (1-335): 1.58e-51: 181: 15.45		HXD4_HUMAN (144-389): 1.64e-36: 135: 26.02
+	Dm
		1096267 HR78_DROME (3-264): 1.1e-56: 198: 20.91		Q9U984_DROME (241-366): 1.06e-30: 116: 26.98
+	Hs
		837977 NR1D2_HUMAN (4-193): 2.04e-50: 181: 24.21		MEOX2_HUMAN (114-366): 8.49e-34: 129: 20.16
+	Hs
		370576 ESR1_HUMAN (3-179): 3.52e-49: 178: 29.94		HXC10_HUMAN (138-358): 2.3e-33: 129: 25.68
+	Ce
		712511 NHR25_CAEEL (3-352): 6.98e-50: 179: 19.77		LIN39_CAEEL (154-357): 7.85e-34: 128: 30.09
+	Mm
		223202 HNF4G_MOUSE (1-257): 1.96e-50: 177: 19.16		TLX3_MOUSE (118-388): 1.11e-31: 123: 16.97
+	Hs
		1151071 Q6NSM0_HUMAN (4-193): 9.86e-49: 172: 24.21		Q6FHY5_HUMAN (114-366): 1.68e-32: 125: 20.16
+	Dm
		447591 HR78_DROME (3-264): 1.1e-56: 198: 20.91		ZEN1_DROME (296-375): 2.29e-18: 87.4: 53.75
+	Dm
		367215 FTZF1_DROME (2-157): 1.13e-44: 168: 25.79		FTZ_DROME (296-353): 9.77e-22: 97.8: 79.31