Interactor 1: CD28 (P10747)
T-cell-specific surface glycoprotein CD28 (TP44) (CD antigen CD28)
Gene: CD28
Interactor 2: P85A (P27986)
Phosphatidylinositol 3-kinase regulatory subunit alpha (PI3-kinase regulatory subunit alpha) (PI3K regulatory subunit alpha) (PtdIns-3-kinase regulatory subunit alpha) (Phosphatidylinositol 3-kinase 85 kDa regulatory subunit alpha) (PI3-kinase subunit p85-alpha) (PtdIns-3-kinase regulatory subunit p85-alpha)
Gene: PIK3R1
Species: Homo sapiens
Source: mint
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.97 | 0.60 | 0.764 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 17242350, 8183372, 27927989, 8621607, 11526404, 24475931, 7509360, 7957566, 8164687, 9820515, 35429500, 19190244, 18641334, 10820259, 7568038, 7807015, 8146197, 7584133, 9417079 |
| Identification Methods | affinity chromatography technology, pull down, x-ray crystallography, unspecified method, anti tag coimmunoprecipitation, coimmunoprecipitation, competition binding |
| Interaction Type | physical association, direct interaction, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | - |
| Common GO terms | GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0006366 - transcription by RNA polymerase II GO:0043066 - negative regulation of apoptotic process GO:0043491 - phosphatidylinositol 3-kinase/protein kinase B signal transduction and 1 others more... |
| Homologous interactions | 6 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
