Interactor 1: IL1B (P10749)
Interleukin-1 beta (IL-1 beta)
Gene: IL1B

Interactor 2: RIPK1 (Q60855)
Receptor-interacting serine/threonine-protein kinase 1 (EC 2.7.11.1) (Cell death protein RIP) (Receptor-interacting protein 1) (RIP-1)
Gene: RIPK1

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 0.60 0.479

The method score is based on:

Property Details
Experiments 25607459
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0001934 - positive regulation of protein phosphorylation
GO:0006954 - inflammatory response
GO:0032757 - positive regulation of interleukin-8 production
GO:0043065 - positive regulation of apoptotic process
GO:0043123 - positive regulation of canonical NF-kappaB signal transduction
and 5 others

more...

Homologous interactions 4

Homologous interactions

Color coding for hit scores

1 269
Mm

1 656
+ Hs
+ Hs
+ Hs
+ Mm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024