HitPredict

Interactor 1: CH60 (P10809)
60 kDa heat shock protein, mitochondrial (EC 5.6.1.7) (60 kDa chaperonin) (Chaperonin 60) (CPN60) (Heat shock protein 60) (HSP-60) (Hsp60) (Heat shock protein family D member 1) (HuCHA60) (Mitochondrial matrix protein P1) (P60 lymphocyte protein)
Gene: HSPD1

Interactor 2: GRP75 (P38646)
Stress-70 protein, mitochondrial (75 kDa glucose-regulated protein) (GRP-75) (Heat shock 70 kDa protein 9) (Heat shock protein family A member 9) (Mortalin) (MOT) (Peptide-binding protein 74) (PBP74)
Gene: HSPA9

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.60	0.60	0.601

The method score is based on:

Property	Details
Experiments	30021884, 37071682
Identification Methods	proximity labelling technology, cross-linking study
Interaction Type	physical association

The annotation score is based on:

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005524 - ATP binding GO:0005737 - cytoplasm GO:0005739 - mitochondrion GO:0005743 - mitochondrial inner membrane and 8 others more... GO:0005759 - mitochondrial matrix GO:0016887 - ATP hydrolysis activity GO:0031625 - ubiquitin protein ligase binding GO:0042026 - protein refolding GO:0043066 - negative regulation of apoptotic process GO:0051082 - unfolded protein binding GO:0070062 - extracellular exosome GO:0140662 - ATP-dependent protein folding chaperone
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1	573
Hs

1	679

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024