Interactor 1: IRGM (A1A4Y4)
Immunity-related GTPase family M protein (EC 3.6.5.-) (Immunity-related GTPase family M protein 1) (Interferon-inducible protein 1) (LPS-stimulated RAW 264.7 macrophage protein 47 homolog) (LRG-47)
Gene: IRGM
Interactor 2: BECN1 (Q14457)
Beclin-1 (Coiled-coil myosin-like BCL2-interacting protein) (Protein GT197) [Cleaved into: Beclin-1-C 35 kDa; Beclin-1-C 37 kDa]
Gene: BECN1
Species: Homo sapiens
Source: biogrid
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.38 | 0.55 | 0.458 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 25891078 |
| Identification Methods | affinity chromatography technology |
| Interaction Type | physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | - |
| Common GO terms | GO:0000045 - autophagosome assembly GO:0005789 - endoplasmic reticulum membrane GO:0005829 - cytosol GO:0010508 - positive regulation of autophagy GO:0019901 - protein kinase binding and 3 others more... |
| Homologous interactions | 0 |
Service provided by Combinatics, Japan
Last updated: 11Aug2025
