HitPredict

Interactor 1: MEX3A (A1L020)
RNA-binding protein MEX3A (RING finger and KH domain-containing protein 4)
Gene: MEX3A

Interactor 2: DDX3X (O00571)
ATP-dependent RNA helicase DDX3X (EC 3.6.4.13) (CAP-Rf) (DEAD box protein 3, X-chromosomal) (DEAD box, X isoform) (DBX) (Helicase-like protein 2) (HLP2)
Gene: DDX3X

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	29395067
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005829 - cytosol
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 520 Hs			1 662
+	Hs
		134079 MEX3C_HUMAN (100-520): 7.78e-102: 321: 47.84		DDX3X_HUMAN (1-662): 0: 614: 100.00
+	Hs
		134054 PCBP1_HUMAN (131-456): 3.05e-66: 220: 16.09		DDX3X_HUMAN (1-662): 0: 614: 100.00
+	Hs
		181700 PCBP1_HUMAN (131-456): 3.05e-66: 220: 16.09		DDX3Y_HUMAN (1-662): 0: 602: 91.84
+	Hs
		571485 MEX3C_HUMAN (100-520): 7.78e-102: 321: 47.84		DDX5_HUMAN (90-658): 2.78e-160: 476: 35.70
+	Hs
		1137391 MEX3C_HUMAN (100-520): 7.78e-102: 321: 47.84		DDX17_HUMAN (122-661): 2.1e-152: 459: 36.38
+	Hs
		134268 IF2B2_HUMAN (118-287): 1.22e-23: 106: 19.55		DDX3X_HUMAN (1-662): 0: 614: 100.00
+	Hs
		127936 IF2B3_HUMAN (40-296): 1.83e-21: 99: 12.04		DDX3X_HUMAN (1-662): 0: 614: 100.00
+	Hs
		571464 PCBP1_HUMAN (131-456): 3.05e-66: 220: 16.09		DDX5_HUMAN (90-658): 2.78e-160: 476: 35.70
+	Hs
		134166 FUBP3_HUMAN (32-371): 1.53e-15: 81.5: 17.65		DDX3X_HUMAN (1-662): 0: 614: 100.00
+	Hs
		134157 FUBP1_HUMAN (75-295): 1.11e-13: 75.7: 19.75		DDX3X_HUMAN (1-662): 0: 614: 100.00
+	Hs
		134229 IF2B1_HUMAN (141-293): 4.15e-12: 70.7: 20.37		DDX3X_HUMAN (1-662): 0: 614: 100.00
+	Mm
		904267 HNRPK_MOUSE (11-429): 7.43e-12: 69.5: 12.11		DDX3X_MOUSE (1-662): 0: 611: 98.64
+	Hs
		128019 IF2B3_HUMAN (40-296): 1.83e-21: 99: 12.04		DDX5_HUMAN (90-658): 2.78e-160: 476: 35.70
+	Hs
		128255 IF2B3_HUMAN (40-296): 1.83e-21: 99: 12.04		DDX17_HUMAN (122-661): 2.1e-152: 459: 36.38
+	Hs
		571615 IF2B1_HUMAN (141-293): 4.15e-12: 70.7: 20.37		DDX5_HUMAN (90-658): 2.78e-160: 476: 35.70
+	Hs
		571383 HNRPK_HUMAN (11-429): 7.43e-12: 69.5: 12.11		DDX5_HUMAN (90-658): 2.78e-160: 476: 35.70
+	Rn
		904402 HNRPK_RAT (11-429): 7.43e-12: 69.5: 12.11		Q6AYI1_RAT (90-658): 4.06e-160: 475: 35.70
+	Hs
		904065 HNRPK_HUMAN (11-429): 7.43e-12: 69.5: 12.11		DDX17_HUMAN (122-661): 2.1e-152: 459: 36.38
+	Mm
		904255 HNRPK_MOUSE (11-429): 7.43e-12: 69.5: 12.11		DDX17_MOUSE (122-650): 1.24e-151: 455: 36.61