Interactor 1: ACRA (P0AE06)
Multidrug efflux pump subunit AcrA (AcrAB-TolC multidrug efflux pump subunit AcrA) (Acridine resistance protein A)
Gene: ACRA

Interactor 2: ACRB (P31224)
Multidrug efflux pump subunit AcrB (AcrAB-TolC multidrug efflux pump subunit AcrB) (Acridine resistance protein B)
Gene: ACRB

Species: Escherichia coli K-12

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 10920254
Identification Methods anti tag coimmunoprecipitation
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains ACR_tran~CusB_dom_1
Common GO terms GO:0005886 - plasma membrane
GO:0009410 - response to xenobiotic stimulus
GO:0009636 - response to toxic substance
GO:0015125 - bile acid transmembrane transporter activity
GO:0015567 - alkane transmembrane transporter activity
and 8 others

more...

Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 397
Ec

1 1049
+ Pa
+ Ec

Service provided by Combinatics, Japan

Last updated: 11Aug2025