HitPredict

Interactor 1: MEX3A (A1L020)
RNA-binding protein MEX3A (RING finger and KH domain-containing protein 4)
Gene: MEX3A

Interactor 2: FMR1 (Q06787)
Fragile X messenger ribonucleoprotein 1 (Fragile X messenger ribonucleoprotein) (FMRP) (Protein FMR-1)
Gene: FMR1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	29395067
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	KH_1~KH_1
Common GO terms	GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005829 - cytosol
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 520 Hs			1 632
+	Mm
		729432 PCBP1_MOUSE (131-456): 3.05e-66: 220: 16.09		FMR1_MOUSE (1-632): 0: 1063: 93.99
+	Hs
		989222 IF2B2_HUMAN (118-287): 1.22e-23: 106: 19.55		FMR1_HUMAN (1-632): 0: 1106: 100.00
+	Hs
		128147 IF2B3_HUMAN (40-296): 1.83e-21: 99: 12.04		FMR1_HUMAN (1-632): 0: 1106: 100.00
+	Hs
		989056 FUBP3_HUMAN (32-371): 1.53e-15: 81.5: 17.65		FMR1_HUMAN (1-632): 0: 1106: 100.00
+	Hs
		989047 FUBP1_HUMAN (75-295): 1.11e-13: 75.7: 19.75		FMR1_HUMAN (1-632): 0: 1106: 100.00
+	Hs
		988961 MEX3B_HUMAN (32-193): 1.41e-12: 71.8: 28.21		FMR1_HUMAN (1-632): 0: 1106: 100.00
+	Hs
		989156 IF2B1_HUMAN (141-293): 4.15e-12: 70.7: 20.37		FMR1_HUMAN (1-632): 0: 1106: 100.00
+	Hs
		903897 HNRPK_HUMAN (11-429): 7.43e-12: 69.5: 12.11		FMR1_HUMAN (1-632): 0: 1106: 100.00
+	Mm
		729463 FUBP2_MOUSE (190-302): 9.72e-09: 59.9: 22.03		FMR1_MOUSE (1-632): 0: 1063: 93.99
+	Mm
		888821 PCBP1_MOUSE (131-456): 3.05e-66: 220: 16.09		Q8BPK8_MOUSE (1-357): 0: 688: 97.76
+	Mm
		1112169 FUBP2_MOUSE (190-302): 9.72e-09: 59.9: 22.03		Q8BPK8_MOUSE (1-357): 0: 688: 97.76
+	Hs
		843848 FUBP3_HUMAN (32-371): 1.53e-15: 81.5: 17.65		FXR1_HUMAN (1-334): 0: 604: 73.95
+	Hs
		843831 FUBP1_HUMAN (75-295): 1.11e-13: 75.7: 19.75		FXR1_HUMAN (1-334): 0: 604: 73.95
+	Hs
		843751 MEX3B_HUMAN (32-193): 1.41e-12: 71.8: 28.21		FXR1_HUMAN (1-334): 0: 604: 73.95
+	Mm
		904263 HNRPK_MOUSE (11-429): 7.43e-12: 69.5: 12.11		FXR1_MOUSE (1-334): 0: 596: 73.65
+	Hs
		844076 PCBP1_HUMAN (131-456): 3.05e-66: 220: 16.09		FXR2_HUMAN (268-525): 3.17e-50: 186: 30.56
+	Hs
		844194 FUBP3_HUMAN (32-371): 1.53e-15: 81.5: 17.65		FXR2_HUMAN (268-525): 3.17e-50: 186: 30.56
+	Hs
		844181 FUBP1_HUMAN (75-295): 1.11e-13: 75.7: 19.75		FXR2_HUMAN (268-525): 3.17e-50: 186: 30.56
+	Hs
		844116 MEX3B_HUMAN (32-193): 1.41e-12: 71.8: 28.21		FXR2_HUMAN (268-525): 3.17e-50: 186: 30.56