Interactor 1: CD14 (P10810)
Monocyte differentiation antigen CD14 (Myeloid cell-specific leucine-rich glycoprotein) (CD antigen CD14)
Gene: CD14

Interactor 2: TLR8 (P58682)
Toll-like receptor 8 (CD antigen CD288)
Gene: TLR8

Species: Mus musculus

Source: innatedb

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 21078886
Identification Methods tandem affinity purification
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains LRR_1~LRR_5, LRR_1~LRR_8
Common GO terms GO:0006954 - inflammatory response
GO:0009897 - external side of plasma membrane
GO:0032729 - positive regulation of type II interferon production
GO:0032757 - positive regulation of interleukin-8 production
GO:0045087 - innate immune response
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 366
Mm

1 1032
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Last updated: 15 Jul 2024