Interactor 1: CD14 (P10810)
Monocyte differentiation antigen CD14 (Myeloid cell-specific leucine-rich glycoprotein) (CD antigen CD14)
Gene: CD14

Interactor 2: TLR9 (Q9EQU3)
Toll-like receptor 9 (CD antigen CD289)
Gene: TLR9

Species: Mus musculus

Source: innatedb

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 21078886
Identification Methods tandem affinity purification
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains LRR_1~LRR_8
Common GO terms GO:0001819 - positive regulation of cytokine production
GO:0002237 - response to molecule of bacterial origin
GO:0032729 - positive regulation of type II interferon production
GO:0032757 - positive regulation of interleukin-8 production
GO:0032760 - positive regulation of tumor necrosis factor production
and 2 others

more...

Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 366
Mm

1 1032
+ Hs
+ Hs
+ Hs
+ Mm
+ Mm
+ Hs
+ At
+ Mm
+ Hs
+ Hs
+ Mm
+ At
+ Hs
+ Hs
+ Hs
+ Hs
+ Zm
+ At
+ At
+ Dr

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024