Interactor 1: CD14 (P10810)
Monocyte differentiation antigen CD14 (Myeloid cell-specific leucine-rich glycoprotein) (CD antigen CD14)
Gene: CD14

Interactor 2: TLR4 (Q9QUK6)
Toll-like receptor 4 (CD antigen CD284)
Gene: TLR4

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 12196527
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains LRR_1~LRR_8
Common GO terms GO:0001530 - lipopolysaccharide binding
GO:0001875 - lipopolysaccharide immune receptor activity
GO:0006954 - inflammatory response
GO:0009617 - response to bacterium
GO:0009897 - external side of plasma membrane
and 10 others

more...

Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 366
Mm

1 835
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024