HitPredict

Interactor 1: THA (P10827)
Thyroid hormone receptor alpha (Nuclear receptor subfamily 1 group A member 1) (V-erbA-related protein 7) (EAR-7) (c-erbA-1) (c-erbA-alpha)
Gene: THRA

Interactor 2: AMOT (Q4VCS5)
Angiomotin
Gene: AMOT

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.48	0.60	0.541

Property	Details
Experiments	23414517
Identification Methods	two hybrid, two hybrid fragment pooling approach
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 490 Hs			1 1084
+	Hs
		500450 THA_HUMAN (1-490): 1.27e-155: 453: 100.00		AMOL2_HUMAN (296-902): 3.42e-27: 121: 39.81
+	Hs
		369789 ESR1_HUMAN (1-442): 2.2e-108: 336: 19.04		MRCKA_HUMAN (257-924): 1.39e-36: 152: 10.38
+	Hs
		370723 ESR1_HUMAN (1-442): 2.2e-108: 336: 19.04		CE164_HUMAN (20-1032): 2.66e-35: 148: 11.99
+	Hs
		587141 RXRA_HUMAN (6-409): 6.39e-113: 343: 24.69		SMCA4_HUMAN (46-592): 7.62e-32: 137: 12.59
+	Hs
		369214 ESR1_HUMAN (1-442): 2.2e-108: 336: 19.04		SMCA4_HUMAN (46-592): 7.62e-32: 137: 12.59
+	Mm
		1142657 ERR2_MOUSE (1-409): 3.66e-101: 312: 21.41		FKB15_MOUSE (247-1080): 4.45e-38: 157: 13.19
+	Hs
		370586 ESR1_HUMAN (1-442): 2.2e-108: 336: 19.04		ITSN2_HUMAN (192-932): 2.36e-30: 132: 10.74
+	Hs
		846907 NR1H2_HUMAN (5-406): 3.92e-107: 328: 23.99		SMCA4_HUMAN (46-592): 7.62e-32: 137: 12.59
+	Hs
		782504 HNF4A_HUMAN (8-451): 1.23e-104: 322: 21.87		SMCA4_HUMAN (46-592): 7.62e-32: 137: 12.59
+	Mm
		1111929 ERR2_MOUSE (1-409): 3.66e-101: 312: 21.41		SMCA4_MOUSE (46-592): 1.64e-32: 139: 12.94
+	Hs
		370819 ESR1_HUMAN (1-442): 2.2e-108: 336: 19.04		MRCKB_HUMAN (223-790): 7.52e-19: 95: 8.90
+	Hs
		659748 RXRB_HUMAN (6-415): 6.8e-109: 335: 23.36		MRCKB_HUMAN (223-790): 7.52e-19: 95: 8.90
+	Mm
		740784 THB_MOUSE (13-404): 6.61e-113: 342: 69.80		MYH9_MOUSE (51-655): 2.19e-15: 83.8: 9.15
+	Hs
		587127 RXRA_HUMAN (6-409): 6.39e-113: 343: 24.69		MYH9_HUMAN (51-655): 1.51e-14: 81.1: 9.31
+	Hs
		368902 ESR1_HUMAN (1-442): 2.2e-108: 336: 19.04		MYH6_HUMAN (273-669): 1.82e-15: 83.8: 10.08
+	Hs
		369096 ESR1_HUMAN (1-442): 2.2e-108: 336: 19.04		MYH9_HUMAN (51-655): 1.51e-14: 81.1: 9.31
+	Hs
		148263 ESR1_HUMAN (1-442): 2.2e-108: 336: 19.04		CTRO_HUMAN (533-815): 3.66e-12: 73.4: 12.37
+	Hs
		370609 ESR1_HUMAN (1-442): 2.2e-108: 336: 19.04		RRBP1_HUMAN (179-773): 3.57e-12: 73: 12.40
+	Hs
		369786 ESR1_HUMAN (1-442): 2.2e-108: 336: 19.04		CROCC_HUMAN (247-925): 1.51e-09: 64.6: 9.95
+	Hs
		782578 HNF4A_HUMAN (8-451): 1.23e-104: 322: 21.87		SRCAP_HUMAN (828-1033): 1.6e-09: 64.6: 21.40