Interactor 1: THA (P10827)
Thyroid hormone receptor alpha (Nuclear receptor subfamily 1 group A member 1) (V-erbA-related protein 7) (EAR-7) (c-erbA-1) (c-erbA-alpha)
Gene: THRA

Interactor 2: MED16 (Q9Y2X0)
Mediator of RNA polymerase II transcription subunit 16 (Mediator complex subunit 16) (Thyroid hormone receptor-associated protein 5) (Thyroid hormone receptor-associated protein complex 95 kDa component) (Trap95) (Vitamin D3 receptor-interacting protein complex 92 kDa component) (DRIP92)
Gene: MED16

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.54 0.60 0.571

The method score is based on:

Property Details
Experiments 8710870, 10198638
Identification Methods biochemical, affinity chromatography technology
Interaction Type association, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0006357 - regulation of transcription by RNA polymerase II
GO:0006366 - transcription by RNA polymerase II
Homologous interactions 4

Homologous interactions

Color coding for hit scores

1 490
Hs

1 877
+ Hs
+ Hs
+ Mm
+ Mm

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Last updated: 15 Jul 2024