HitPredict

Interactor 1: H2B1F (P10853)
Histone H2B type 1-F/J/L (H2B 291A)
Gene: H2bc7

Interactor 2: UHRF1 (Q8VDF2)
E3 ubiquitin-protein ligase UHRF1 (EC 2.3.2.27) (Nuclear protein 95) (Nuclear zinc finger protein Np95) (RING-type E3 ubiquitin transferase UHRF1) (Ubiquitin-like PHD and RING finger domain-containing protein 1) (mUhrf1) (Ubiquitin-like-containing PHD and RING finger domains protein 1)
Gene: UHRF1

Species: Mus musculus

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.47	1.00	0.692

Property	Details
Experiments	14993289
Identification Methods	experimental interaction detection, far western blotting
Interaction Type	ubiquitination reaction, direct interaction

Property	Details
Interacting Pfam domains	Histone~ubiquitin
Common GO terms	GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 126 Mm			1 782
+	Hs
		1087358 H2B2E_HUMAN (1-126): 4.55e-54: 167: 98.41		UHRF1_HUMAN (1-782): 0: 899: 72.94
+	Hs
		707721 H2B1B_HUMAN (1-126): 1.26e-53: 166: 96.83		UHRF1_HUMAN (1-782): 0: 899: 72.94
+	Hs
		918629 H2B1C_HUMAN (1-126): 9.18e-54: 166: 99.21		UHRF1_HUMAN (1-782): 0: 899: 72.94
+	Hs
		1018625 H2B1H_HUMAN (1-126): 4.36e-54: 167: 98.41		CHD3_HUMAN (209-507): 4.06e-54: 205: 16.67
+	Hs
		241517 H2B1K_HUMAN (1-126): 1e-53: 166: 98.41		CHD3_HUMAN (209-507): 4.06e-54: 205: 16.67
+	Hs
		707612 H2B1B_HUMAN (1-126): 1.26e-53: 166: 96.83		CHD3_HUMAN (209-507): 4.06e-54: 205: 16.67
+	Hs
		918325 H2B1C_HUMAN (1-126): 9.18e-54: 166: 99.21		CHD3_HUMAN (209-507): 4.06e-54: 205: 16.67
+	Hs
		241591 H2B1K_HUMAN (1-126): 1e-53: 166: 98.41		CHD5_HUMAN (260-507): 2.57e-50: 193: 18.85
+	Hs
		918541 H2B1C_HUMAN (1-126): 9.18e-54: 166: 99.21		CHD5_HUMAN (260-507): 2.57e-50: 193: 18.85
+	Hs
		1059648 H2B2E_HUMAN (1-126): 4.55e-54: 167: 98.41		CHD4_HUMAN (260-507): 1.03e-45: 179: 16.17
+	Hs
		1059777 H2B1H_HUMAN (1-126): 4.36e-54: 167: 98.41		CHD4_HUMAN (260-507): 1.03e-45: 179: 16.17
+	Hs
		241527 H2B1K_HUMAN (1-126): 1e-53: 166: 98.41		CHD4_HUMAN (260-507): 1.03e-45: 179: 16.17
+	Hs
		707635 H2B1B_HUMAN (1-126): 1.26e-53: 166: 96.83		CHD4_HUMAN (260-507): 1.03e-45: 179: 16.17
+	Hs
		918368 H2B1C_HUMAN (1-126): 9.18e-54: 166: 99.21		CHD4_HUMAN (260-507): 1.03e-45: 179: 16.17
+	Hs
		886109 H2B1D_HUMAN (1-126): 2.6e-53: 165: 98.41		CHD4_HUMAN (260-507): 1.03e-45: 179: 16.17
+	Hs
		1059827 H2B1L_HUMAN (1-126): 1.57e-52: 163: 99.21		CHD4_HUMAN (260-507): 1.03e-45: 179: 16.17
+	Hs
		1087459 H2B2E_HUMAN (1-126): 4.55e-54: 167: 98.41		KDM5B_HUMAN (222-399): 4.9e-35: 146: 19.89
+	Hs
		1274470 H2B1H_HUMAN (1-126): 4.36e-54: 167: 98.41		BAZ2B_HUMAN (315-414): 1.22e-20: 99: 28.97
+	Hs
		152598 H2B1B_HUMAN (1-126): 1.26e-53: 166: 96.83		KMT2D_HUMAN (318-370): 1.98e-11: 70.3: 46.30
+	Dm
		355270 H2B_DROME (36-126): 8.04e-47: 148: 94.51		Q9V9T4_DROME (316-369): 2.29e-15: 83: 50.00