HitPredict

Interactor 1: RAD18 (P10862)
Postreplication repair E3 ubiquitin-protein ligase RAD18 (EC 2.3.2.27) (RING-type E3 ubiquitin transferase RAD18) (Radiation sensitivity protein 18)
Gene: RAD18

Interactor 2: SSB1 (P11484)
Ribosome-associated molecular chaperone SSB1 (EC 3.6.4.10) (Cold-inducible protein YG101) (Heat shock protein SSB1) (Hsp70 chaperone Ssb)
Gene: SSB1

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	19536198
Identification Methods	tandem affinity purification
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 487 Sc			1 613
+	Sc
		769768 PSH1_YEAST (14-175): 3.76e-39: 148: 21.30		SSB2_YEAST (1-613): 0: 1118: 99.35
+	Hs
		563999 RO52_HUMAN (15-392): 1.57e-94: 296: 12.38		HSP76_HUMAN (3-612): 0: 901: 58.66
+	Hs
		504715 TRIM6_HUMAN (14-400): 3.65e-76: 248: 11.16		HSP7C_HUMAN (5-612): 0: 900: 59.84
+	Hs
		1120600 TRI17_HUMAN (14-433): 1.42e-69: 231: 10.43		Q53FC7_HUMAN (3-612): 0: 897: 58.33
+	Hs
		135007 TRI38_HUMAN (15-400): 4.64e-65: 219: 11.34		HSP7C_HUMAN (5-612): 0: 900: 59.84
+	Hs
		135010 TRI38_HUMAN (15-400): 4.64e-65: 219: 11.34		HS71L_HUMAN (5-612): 0: 896: 59.34
+	Hs
		135015 TRI38_HUMAN (15-400): 4.64e-65: 219: 11.34		HSP72_HUMAN (4-612): 0: 891: 59.97
+	Hs
		504714 TRIM7_HUMAN (23-392): 6.86e-59: 204: 11.66		HSP7C_HUMAN (5-612): 0: 900: 59.84
+	Hs
		503987 TRI26_HUMAN (15-334): 1.92e-51: 184: 11.94		HSP7C_HUMAN (5-612): 0: 900: 59.84
+	Hs
		504072 TRI25_HUMAN (16-318): 5.6e-39: 151: 15.19		HSP7C_HUMAN (5-612): 0: 900: 59.84
+	Hs
		713970 TRI25_HUMAN (16-318): 5.6e-39: 151: 15.19		HS71L_HUMAN (5-612): 0: 896: 59.34
+	Hs
		564131 COP1_HUMAN (16-349): 2.62e-36: 144: 16.27		HSP76_HUMAN (3-612): 0: 901: 58.66
+	Hs
		504433 COP1_HUMAN (16-349): 2.62e-36: 144: 16.27		HSP7C_HUMAN (5-612): 0: 900: 59.84
+	Hs
		871567 TRI25_HUMAN (16-318): 5.6e-39: 151: 15.19		HSP72_HUMAN (4-612): 0: 891: 59.97
+	Hs
		564176 TRI31_HUMAN (21-323): 3.03e-35: 137: 11.82		HSP76_HUMAN (3-612): 0: 901: 58.66
+	Hs
		504712 TRI31_HUMAN (21-323): 3.03e-35: 137: 11.82		HSP7C_HUMAN (5-612): 0: 900: 59.84
+	Hs
		871685 COP1_HUMAN (16-349): 2.62e-36: 144: 16.27		HSP72_HUMAN (4-612): 0: 891: 59.97
+	Sc
		450235 PSH1_YEAST (14-175): 3.76e-39: 148: 21.30		HSP73_YEAST (9-611): 0: 677: 60.66