HitPredict

Interactor 1: RAD18 (P10862)
Postreplication repair E3 ubiquitin-protein ligase RAD18 (EC 2.3.2.27) (RING-type E3 ubiquitin transferase RAD18) (Radiation sensitivity protein 18)
Gene: RAD18

Interactor 2: PCNA (P15873)
Proliferating cell nuclear antigen (PCNA)
Gene: POL30

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.96	0.60	0.760

Property	Details
Experiments	23034805, 18485869, 35338218, 16611731, 16957771, 18385374, 24224485, 27707542, 32341533, 32228444, 33570581, 16344468, 19851286
Identification Methods	pull down, two hybrid, enzymatic study
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0006301 - postreplication repair GO:0070987 - error-free translesion synthesis
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 487 Sc			1 258
+	Hs
		517490 RAD18_HUMAN (16-437): 6.5e-61: 209: 20.73		PCNA_HUMAN (1-258): 2.37e-109: 317: 35.52
+	Hs
		517227 TRI26_HUMAN (15-334): 1.92e-51: 184: 11.94		PCNA_HUMAN (1-258): 2.37e-109: 317: 35.52
+	Hs
		517254 TRI25_HUMAN (16-318): 5.6e-39: 151: 15.19		PCNA_HUMAN (1-258): 2.37e-109: 317: 35.52
+	Hs
		517448 TRI31_HUMAN (21-323): 3.03e-35: 137: 11.82		PCNA_HUMAN (1-258): 2.37e-109: 317: 35.52