HitPredict

Interactor 1: RAD18 (P10862)
Postreplication repair E3 ubiquitin-protein ligase RAD18 (EC 2.3.2.27) (RING-type E3 ubiquitin transferase RAD18) (Radiation sensitivity protein 18)
Gene: RAD18

Interactor 2: UBC9 (P50623)
SUMO-conjugating enzyme UBC9 (EC 2.3.2.-) (RING-type E3 SUMO transferase UBC9) (Ubiquitin carrier protein 9) (Ubiquitin-conjugating enzyme E2-18 kDa) (Ubiquitin-protein ligase)
Gene: UBC9

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.74	1.00	0.863

Property	Details
Experiments	23034805, 24224485, 12226657
Identification Methods	pull down, two hybrid, enzymatic study, affinity chromatography technology
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	UQ_con~zf-C3HC4_2
Common GO terms	GO:0005634 - nucleus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 487 Sc			1 157
+	Hs
		584907 RO52_HUMAN (15-392): 1.57e-94: 296: 12.38		UB2D1_HUMAN (4-156): 1.54e-73: 218: 33.99
+	Hs
		584923 RO52_HUMAN (15-392): 1.57e-94: 296: 12.38		UB2D2_HUMAN (4-156): 2.79e-73: 217: 32.68
+	Hs
		584916 RO52_HUMAN (15-392): 1.57e-94: 296: 12.38		UB2D3_HUMAN (4-156): 3.32e-72: 215: 32.68
+	Hs
		584926 RO52_HUMAN (15-392): 1.57e-94: 296: 12.38		UBC9_HUMAN (1-156): 5.53e-69: 207: 56.41
+	Hs
		584910 RO52_HUMAN (15-392): 1.57e-94: 296: 12.38		UB2E1_HUMAN (3-156): 3.29e-66: 201: 31.82
+	Hs
		1336390 TRI39_HUMAN (19-416): 1.51e-78: 256: 10.43		UB2D4_HUMAN (4-156): 2.62e-74: 220: 33.33
+	Hs
		895815 TRI68_HUMAN (17-392): 1.08e-80: 260: 11.97		UB2D3_HUMAN (4-156): 3.32e-72: 215: 32.68
+	Hs
		849453 TRI39_HUMAN (19-416): 1.51e-78: 256: 10.43		UB2D1_HUMAN (4-156): 1.54e-73: 218: 33.99
+	Hs
		919870 TRI39_HUMAN (19-416): 1.51e-78: 256: 10.43		UB2D2_HUMAN (4-156): 2.79e-73: 217: 32.68
+	Hs
		895921 TRI39_HUMAN (19-416): 1.51e-78: 256: 10.43		UB2D3_HUMAN (4-156): 3.32e-72: 215: 32.68
+	Hs
		584994 RO52_HUMAN (15-392): 1.57e-94: 296: 12.38		Q7KZS0_HUMAN (1-134): 6.66e-54: 170: 59.70
+	Hs
		895851 TRI58_HUMAN (17-400): 3.21e-77: 251: 12.97		UB2D3_HUMAN (4-156): 3.32e-72: 215: 32.68
+	Hs
		1297370 TRI39_HUMAN (19-416): 1.51e-78: 256: 10.43		UB2E2_HUMAN (3-156): 4.04e-68: 206: 31.17
+	Hs
		1282350 TRI39_HUMAN (19-416): 1.51e-78: 256: 10.43		UB2E3_HUMAN (3-156): 1.16e-67: 205: 31.17
+	Hs
		536760 TRI27_HUMAN (15-391): 1.4e-73: 243: 9.09		UB2D1_HUMAN (4-156): 1.54e-73: 218: 33.99
+	Hs
		536779 TRI27_HUMAN (15-391): 1.4e-73: 243: 9.09		UB2D2_HUMAN (4-156): 2.79e-73: 217: 32.68
+	Hs
		536772 TRI27_HUMAN (15-391): 1.4e-73: 243: 9.09		UB2D3_HUMAN (4-156): 3.32e-72: 215: 32.68
+	Hs
		851889 TRI39_HUMAN (19-416): 1.51e-78: 256: 10.43		UB2E1_HUMAN (3-156): 3.29e-66: 201: 31.82
+	Hs
		536757 TRI27_HUMAN (15-391): 1.4e-73: 243: 9.09		UBE2A_HUMAN (1-154): 1.04e-66: 201: 38.96
+	Hs
		536763 TRI27_HUMAN (15-391): 1.4e-73: 243: 9.09		UB2E1_HUMAN (3-156): 3.29e-66: 201: 31.82