HitPredict

Interactor 1: CXCL2 (P10889)
C-X-C motif chemokine 2 (Macrophage inflammatory protein 2) (MIP2)
Gene: CXCL2

Interactor 2: TF65 (Q04207)
Transcription factor p65 (Nuclear factor NF-kappa-B p65 subunit) (Nuclear factor of kappa light polypeptide gene enhancer in B-cells 3)
Gene: Rela

Species: Mus musculus

Source: innatedb

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.68	0.60	0.640

Property	Details
Experiments	16166627, 15226358, 21825016
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0006954 - inflammatory response GO:0071222 - cellular response to lipopolysaccharide
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 100 Mm			1 549
+	Mm
		522399 GROA_MOUSE (26-96): 5.83e-27: 96.6: 69.01		TF65_MOUSE (1-549): 0: 662: 100.00
+	Mm
		568050 CXL10_MOUSE (10-96): 2.6e-24: 89.7: 28.09		TF65_MOUSE (1-549): 0: 662: 100.00
+	Hs
		587778 CXCL2_HUMAN (22-100): 2.38e-28: 100: 63.29		TF65_HUMAN (1-549): 0: 631: 87.52
+	Hs
		448997 GROA_HUMAN (30-100): 1.73e-26: 95.5: 66.20		TF65_HUMAN (1-549): 0: 631: 87.52
+	Hs
		587791 CXCL3_HUMAN (30-100): 3.51e-26: 94.7: 69.01		TF65_HUMAN (1-549): 0: 631: 87.52
+	Hs
		486198 IL8_HUMAN (31-100): 4.63e-23: 86.6: 43.66		TF65_HUMAN (1-549): 0: 631: 87.52
+	Hs
		364112 CXL10_HUMAN (10-95): 4.28e-22: 84.3: 26.14		TF65_HUMAN (1-549): 0: 631: 87.52
+	Hs
		150325 CXL11_HUMAN (14-97): 1.29e-21: 82.8: 26.74		TF65_HUMAN (1-549): 0: 631: 87.52
+	Hs
		486199 IL8_HUMAN (31-100): 4.63e-23: 86.6: 43.66		REL_HUMAN (12-491): 8.06e-158: 465: 42.89
+	Hs
		486197 IL8_HUMAN (31-100): 4.63e-23: 86.6: 43.66		RELB_HUMAN (7-453): 8.96e-153: 451: 39.20
+	Hs
		486180 IL8_HUMAN (31-100): 4.63e-23: 86.6: 43.66		NFKB1_HUMAN (5-382): 1.19e-142: 437: 32.93
+	Mm
		223018 CXL13_MOUSE (31-100): 8.46e-20: 78.5: 28.17		RELB_MOUSE (13-453): 7.12e-150: 443: 38.54
+	Hs
		364100 CXL10_HUMAN (10-95): 4.28e-22: 84.3: 26.14		NFKB1_HUMAN (5-382): 1.19e-142: 437: 32.93
+	Hs
		150310 CXL11_HUMAN (14-97): 1.29e-21: 82.8: 26.74		NFKB1_HUMAN (5-382): 1.19e-142: 437: 32.93
+	Hs
		486195 IL8_HUMAN (31-100): 4.63e-23: 86.6: 43.66		NFKB2_HUMAN (6-418): 9.56e-141: 430: 33.79