HitPredict

Interactor 1: CLUS (P10909)
Clusterin (Aging-associated gene 4 protein) (Apolipoprotein J) (Apo-J) (Complement cytolysis inhibitor) (CLI) (Complement-associated protein SP-40,40) (Ku70-binding protein 1) (NA1/NA2) (Sulfated glycoprotein 2) (SGP-2) (Testosterone-repressed prostate message 2) (TRPM-2) [Cleaved into: Clusterin beta chain (ApoJalpha) (Complement cytolysis inhibitor a chain) (SP-40,40 beta-chain); Clusterin alpha chain (ApoJbeta) (Complement cytolysis inhibitor b chain) (SP-40,40 alpha-chain)]
Gene: CLU

Interactor 2: TENA (P24821)
Tenascin (TN) (Cytotactin) (GMEM) (GP 150-225) (Glioma-associated-extracellular matrix antigen) (Hexabrachion) (JI) (Myotendinous antigen) (Neuronectin) (Tenascin-C) (TN-C)
Gene: TNC

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	21349332
Identification Methods	affinity chromatography technology, pull down
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005576 - extracellular region GO:0005615 - extracellular space GO:0010628 - positive regulation of gene expression GO:0062023 - collagen-containing extracellular matrix
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 449 Hs			1 2201
+	Hs
		500803 CLUS_HUMAN (1-449): 0: 697: 100.00		SDK2_HUMAN (1070-2083): 6.32e-103: 372: 10.86
+	Hs
		489887 CLUS_HUMAN (1-449): 0: 697: 100.00		PTPRF_HUMAN (1275-2107): 2.59e-100: 362: 9.89
+	Hs
		500785 CLUS_HUMAN (1-449): 0: 697: 100.00		PTPRS_HUMAN (765-1805): 3.01e-95: 346: 14.45
+	Hs
		500906 CLUS_HUMAN (1-449): 0: 697: 100.00		TEN3_HUMAN (466-622): 4.8e-29: 130: 32.14