HitPredict

Interactor 1: CLUS (P10909)
Clusterin (Aging-associated gene 4 protein) (Apolipoprotein J) (Apo-J) (Complement cytolysis inhibitor) (CLI) (Complement-associated protein SP-40,40) (Ku70-binding protein 1) (NA1/NA2) (Sulfated glycoprotein 2) (SGP-2) (Testosterone-repressed prostate message 2) (TRPM-2) [Cleaved into: Clusterin beta chain (ApoJalpha) (Complement cytolysis inhibitor a chain) (SP-40,40 beta-chain); Clusterin alpha chain (ApoJbeta) (Complement cytolysis inhibitor b chain) (SP-40,40 alpha-chain)]
Gene: CLU

Interactor 2: B2CL1 (Q07817)
Bcl-2-like protein 1 (Bcl2-L-1) (Apoptosis regulator Bcl-X)
Gene: BCL2L1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.61 0.60 0.606

The method score is based on:

Property Details
Experiments 21527247, 21567405
Identification Methods x-ray crystallography, affinity chromatography technology, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation, pull down
Interaction Type association, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0001836 - release of cytochrome c from mitochondria
GO:0005737 - cytoplasm
GO:0005739 - mitochondrion
GO:0005743 - mitochondrial inner membrane
GO:0005829 - cytosol
and 3 others

more...
Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 449
Hs

1 233
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024