HitPredict

Interactor 1: CLUS (P10909)
Clusterin (Aging-associated gene 4 protein) (Apolipoprotein J) (Apo-J) (Complement cytolysis inhibitor) (CLI) (Complement-associated protein SP-40,40) (Ku70-binding protein 1) (NA1/NA2) (Sulfated glycoprotein 2) (SGP-2) (Testosterone-repressed prostate message 2) (TRPM-2) [Cleaved into: Clusterin beta chain (ApoJalpha) (Complement cytolysis inhibitor a chain) (SP-40,40 beta-chain); Clusterin alpha chain (ApoJbeta) (Complement cytolysis inhibitor b chain) (SP-40,40 alpha-chain)]
Gene: CLU

Interactor 2: DDR1 (Q08345)
Epithelial discoidin domain-containing receptor 1 (Epithelial discoidin domain receptor 1) (EC 2.7.10.1) (CD167 antigen-like family member A) (Cell adhesion kinase) (Discoidin receptor tyrosine kinase) (HGK2) (Mammary carcinoma kinase 10) (MCK-10) (Protein-tyrosine kinase 3A) (Protein-tyrosine kinase RTK-6) (TRK E) (Tyrosine kinase DDR) (Tyrosine-protein kinase CAK) (CD antigen CD167a)
Gene: DDR1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	36736316
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005615 - extracellular space GO:0070062 - extracellular exosome
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 449 Hs			1 913
+	Hs
		500801 CLUS_HUMAN (1-449): 0: 697: 100.00		DDR2_HUMAN (20-905): 0: 843: 51.46
+	Hs
		500700 CLUS_HUMAN (1-449): 0: 697: 100.00		FGFR1_HUMAN (540-905): 6.78e-109: 356: 32.52
+	Hs
		500798 CLUS_HUMAN (1-449): 0: 697: 100.00		NTRK3_HUMAN (607-905): 4.06e-67: 242: 43.63
+	Hs
		435508 CLUS_HUMAN (1-449): 0: 697: 100.00		IGF1R_HUMAN (600-908): 4.51e-51: 197: 37.22
+	Rn
		102526 G3V836_RAT (14-449): 0: 688: 75.90		INSR_RAT (600-908): 1.98e-51: 198: 36.25