HitPredict

Interactor 1: CLUS (P10909)
Clusterin (Aging-associated gene 4 protein) (Apolipoprotein J) (Apo-J) (Complement cytolysis inhibitor) (CLI) (Complement-associated protein SP-40,40) (Ku70-binding protein 1) (NA1/NA2) (Sulfated glycoprotein 2) (SGP-2) (Testosterone-repressed prostate message 2) (TRPM-2) [Cleaved into: Clusterin beta chain (ApoJalpha) (Complement cytolysis inhibitor a chain) (SP-40,40 beta-chain); Clusterin alpha chain (ApoJbeta) (Complement cytolysis inhibitor b chain) (SP-40,40 alpha-chain)]
Gene: CLU

Interactor 2: EP300 (Q09472)
Histone acetyltransferase p300 (p300 HAT) (EC 2.3.1.48) (E1A-associated protein p300) (Histone butyryltransferase p300) (EC 2.3.1.-) (Histone crotonyltransferase p300) (EC 2.3.1.-) (Protein 2-hydroxyisobutyryltransferase p300) (EC 2.3.1.-) (Protein lactyltransferas p300) (EC 2.3.1.-) (Protein propionyltransferase p300) (EC 2.3.1.-)
Gene: EP300

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	33742100
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0031333 - negative regulation of protein-containing complex assembly GO:0048156 - tau protein binding and 1 others more... GO:0050821 - protein stabilization
Homologous interactions	3

Homologous interactions

Color coding for hit scores

	1 449 Hs			1 2414
+	Hs
		500795 CLUS_HUMAN (1-449): 0: 697: 100.00		BRD3_HUMAN (1055-1159): 9.06e-30: 130: 30.48
+	Hs
		500794 CLUS_HUMAN (1-449): 0: 697: 100.00		MDC1_HUMAN (455-1061): 8.69e-13: 76.6: 11.82
+	Hs
		500846 CLUS_HUMAN (1-449): 0: 697: 100.00		PHIP_HUMAN (1068-1157): 6.78e-12: 73.6: 42.86