HitPredict

Interactor 1: CLUS (P10909)
Clusterin (Aging-associated gene 4 protein) (Apolipoprotein J) (Apo-J) (Complement cytolysis inhibitor) (CLI) (Complement-associated protein SP-40,40) (Ku70-binding protein 1) (NA1/NA2) (Sulfated glycoprotein 2) (SGP-2) (Testosterone-repressed prostate message 2) (TRPM-2) [Cleaved into: Clusterin beta chain (ApoJalpha) (Complement cytolysis inhibitor a chain) (SP-40,40 beta-chain); Clusterin alpha chain (ApoJbeta) (Complement cytolysis inhibitor b chain) (SP-40,40 alpha-chain)]
Gene: CLU

Interactor 2: DDR2 (Q16832)
Discoidin domain-containing receptor 2 (Discoidin domain receptor 2) (EC 2.7.10.1) (CD167 antigen-like family member B) (Discoidin domain-containing receptor tyrosine kinase 2) (Neurotrophic tyrosine kinase, receptor-related 3) (Receptor protein-tyrosine kinase TKT) (Tyrosine-protein kinase TYRO10) (CD antigen CD167b)
Gene: DDR2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.50	0.558

Property	Details
Experiments	35384245, 36736316
Identification Methods	proximity labelling technology, affinity chromatography technology
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 449 Hs			1 855
+	Hs
		500782 CLUS_HUMAN (1-449): 0: 697: 100.00		DDR1_HUMAN (22-849): 0: 655: 52.08
+	Hs
		500700 CLUS_HUMAN (1-449): 0: 697: 100.00		FGFR1_HUMAN (505-851): 2.72e-102: 337: 32.49
+	Hs
		500798 CLUS_HUMAN (1-449): 0: 697: 100.00		NTRK3_HUMAN (551-849): 3.61e-99: 329: 42.63
+	Hs
		435508 CLUS_HUMAN (1-449): 0: 697: 100.00		IGF1R_HUMAN (535-845): 9.34e-58: 217: 40.13
+	Rn
		102526 G3V836_RAT (14-449): 0: 688: 75.90		INSR_RAT (511-849): 4.34e-54: 206: 37.46