Interactor 1: GHR (P10912)
Growth hormone receptor (GH receptor) (Somatotropin receptor) [Cleaved into: Growth hormone-binding protein (GH-binding protein) (GHBP) (Serum-binding protein)]
Gene: GHR

Interactor 2: PTN3 (P26045)
Tyrosine-protein phosphatase non-receptor type 3 (EC 3.1.3.48) (Protein-tyrosine phosphatase H1) (PTP-H1)
Gene: PTPN3

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.61 1.00 0.785

The method score is based on:

Property Details
Experiments 12907755
Identification Methods pull down, far western blotting, array technology, phosphatase assay
Interaction Type direct interaction, dephosphorylation reaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains PDZ~fn3
Common GO terms GO:0005829 - cytosol
GO:0005886 - plasma membrane
Homologous interactions 16

Homologous interactions

Color coding for hit scores

1 638
Hs

1 913
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024