HitPredict

Interactor 1: GHR (P10912)
Growth hormone receptor (GH receptor) (Somatotropin receptor) [Cleaved into: Growth hormone-binding protein (GH-binding protein) (GHBP) (Serum-binding protein)]
Gene: GHR

Interactor 2: PTN13 (Q12923)
Tyrosine-protein phosphatase non-receptor type 13 (EC 3.1.3.48) (Fas-associated protein-tyrosine phosphatase 1) (FAP-1) (PTP-BAS) (Protein-tyrosine phosphatase 1E) (PTP-E1) (hPTPE1) (Protein-tyrosine phosphatase PTPL1)
Gene: PTPN13

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	1.00	0.647

Property	Details
Experiments	12907755
Identification Methods	far western blotting
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	PDZ~fn3
Common GO terms	GO:0005829 - cytosol GO:0005886 - plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 638 Hs			1 2485
+	Hs
		500946 GHR_HUMAN (1-638): 0: 731: 100.00		PTPRB_HUMAN (953-2481): 3.7e-135: 473: 14.59
+	Mm
		562609 GHR_MOUSE (1-637): 0: 748: 67.85		PTN11_MOUSE (2083-2480): 5.09e-117: 387: 31.47
+	Hs
		500961 GHR_HUMAN (1-638): 0: 731: 100.00		PTPRJ_HUMAN (1183-2475): 1.09e-110: 389: 14.37
+	Hs
		500960 GHR_HUMAN (1-638): 0: 731: 100.00		PTN11_HUMAN (2083-2480): 4.2e-117: 387: 31.47
+	Hs
		500952 GHR_HUMAN (1-638): 0: 731: 100.00		PTN9_HUMAN (2136-2470): 4.76e-112: 372: 27.04
+	Hs
		441167 GHR_HUMAN (1-638): 0: 731: 100.00		PTPRC_HUMAN (2155-2465): 8.58e-71: 265: 24.78
+	Hs
		500966 GHR_HUMAN (1-638): 0: 731: 100.00		PTPRK_HUMAN (2206-2470): 8.98e-55: 214: 23.83
+	Hs
		500973 GHR_HUMAN (1-638): 0: 731: 100.00		PTPRH_HUMAN (2230-2481): 3.22e-50: 198: 41.00
+	Hs
		500942 GHR_HUMAN (1-638): 0: 731: 100.00		PTN2_HUMAN (2231-2465): 3.03e-45: 172: 37.50
+	Hs
		500943 GHR_HUMAN (1-638): 0: 731: 100.00		PTN1_HUMAN (2229-2465): 2.56e-45: 172: 37.40
+	Hs
		500947 GHR_HUMAN (1-638): 0: 731: 100.00		PTN3_HUMAN (1207-1558): 1.58e-17: 91.9: 11.02
+	Hs
		560475 PRLR_HUMAN (44-526): 1.61e-106: 336: 26.02		PTN11_HUMAN (2083-2480): 4.2e-117: 387: 31.47
+	Hs
		581148 EPOR_HUMAN (6-514): 1.3e-51: 187: 14.84		PTPRB_HUMAN (953-2481): 3.7e-135: 473: 14.59
+	Hs
		581162 EPOR_HUMAN (6-514): 1.3e-51: 187: 14.84		PTPRJ_HUMAN (1183-2475): 1.09e-110: 389: 14.37
+	Hs
		581161 EPOR_HUMAN (6-514): 1.3e-51: 187: 14.84		PTN11_HUMAN (2083-2480): 4.2e-117: 387: 31.47
+	Hs
		265768 CRLF1_HUMAN (8-257): 1.99e-55: 195: 19.62		PTPRS_HUMAN (1007-2468): 3.28e-92: 337: 12.77
+	Hs
		441174 EPOR_HUMAN (6-514): 1.3e-51: 187: 14.84		PTPRC_HUMAN (2155-2465): 8.58e-71: 265: 24.78
+	Hs
		581149 EPOR_HUMAN (6-514): 1.3e-51: 187: 14.84		PTPRG_HUMAN (2228-2472): 1.03e-46: 187: 25.87
+	Hs
		581151 EPOR_HUMAN (6-514): 1.3e-51: 187: 14.84		PTN6_HUMAN (2215-2480): 9.54e-47: 181: 40.48
+	Hs
		573561 EPOR_HUMAN (6-514): 1.3e-51: 187: 14.84		PTN1_HUMAN (2229-2465): 2.56e-45: 172: 37.40