HitPredict

Interactor 1: IRF1 (P10914)
Interferon regulatory factor 1 (IRF-1)
Gene: IRF1

Interactor 2: IRF2 (P14316)
Interferon regulatory factor 2 (IRF-2)
Gene: IRF2

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.77 1.00 0.878

The method score is based on:

Property Details
Experiments 16982896, 15241475, 10557076, 8943426
Identification Methods pull down, electrophoretic mobility supershift assay
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains IRF~IRF
Common GO terms GO:0000785 - chromatin
GO:0000977 - RNA polymerase II transcription regulatory region sequence-specific DNA binding
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001228 - DNA-binding transcription activator activity, RNA polymerase II-specific
and 8 others

more...
Homologous interactions 16

Homologous interactions

Color coding for hit scores

1 325
Hs

1 349
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024