Interactor 1: IRF1 (P10914)
Interferon regulatory factor 1 (IRF-1)
Gene: IRF1

Interactor 2: SPI1 (P17947)
Transcription factor PU.1 (31 kDa-transforming protein)
Gene: SPI1

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.69 0.60 0.646

The method score is based on:

Property Details
Experiments 9593745, 11483597
Identification Methods pull down, electrophoretic mobility shift assay, anti tag coimmunoprecipitation
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000785 - chromatin
GO:0000976 - transcription cis-regulatory region binding
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0005634 - nucleus
and 4 others

more...

Homologous interactions 10

Homologous interactions

Color coding for hit scores

1 325
Hs

1 270
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024