HitPredict

Interactor 1: IRF1 (P10914)
Interferon regulatory factor 1 (IRF-1)
Gene: IRF1

Interactor 2: STAT1 (P42224)
Signal transducer and activator of transcription 1-alpha/beta (Transcription factor ISGF-3 components p91/p84)
Gene: STAT1

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.97 0.60 0.766

The method score is based on:

Property Details
Experiments 10764778, 16512786, 14578356, 11909852, 18678606, 17918184, 17016442, 12115600, 11777927, 12077266, 14581002, 15194680, 16195385, 12654826, 11882993, 11601909, 10725732, 19136629, 19482358, 16785527 and 4 others

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Identification Methods affinity chromatography technology, pull down, electrophoretic mobility supershift assay, anti tag coimmunoprecipitation
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000785 - chromatin
GO:0000977 - RNA polymerase II transcription regulatory region sequence-specific DNA binding
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0005634 - nucleus
and 9 others

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Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

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1 750
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Last updated: 15 Jul 2024