HitPredict

Interactor 1: IRF1 (P10914)
Interferon regulatory factor 1 (IRF-1)
Gene: IRF1

Interactor 2: IRF7 (Q92985)
Interferon regulatory factor 7 (IRF-7)
Gene: IRF7

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.70 1.00 0.839

The method score is based on:

Property Details
Experiments 14578356, 10924517, 12077266
Identification Methods electrophoretic mobility supershift assay, affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains IRF~IRF
Common GO terms GO:0000785 - chromatin
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0002376 - immune system process
GO:0002819 - regulation of adaptive immune response
and 12 others

more...
Homologous interactions 15

Homologous interactions

Color coding for hit scores

1 325
Hs

1 503
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024